Mesenchymal stem cells in the bone marrow microenvironment: a double-edged sword for AML
Abstract Mesenchymal stem cells (MSCs) play a pivotal role in supporting acute myeloid leukemia (AML) cell survival, proliferation, and drug resistance through various mechanisms, including the release of soluble factors, direct cell-cell interactions, and the creation of a leukemia-supportive niche...
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| Main Authors: | Mohamed J. Saadh, Nima Torabi Fard, Ahmed Hussein, Amirhossein Mirzazadeh, Mohammad Siavashi, Fatemeh SeyedMoharami, Shekoofeh Noroozi, Hamed Soleimani Samarkhazan |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-06-01
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| Series: | Journal of Cancer Research and Clinical Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00432-025-06244-4 |
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