Pharmacotherapy of plexiform neurofibromas in patients with neurofibromatosis type 1. Possible adverse events and their management

Pharmacotherapy of plexiform neurofibromas in patients with neurofibromatosis type 1. Possible adverse events and their management

Neurofibromatosis type 1 is a multisystem genetic disorder associated with an increased risk of benign and malignant tumors due to mutations in the NF1 gene. Clinical manifestations of the disease vary and depend on the patient’s age. One of the most common complications of neurofibromatosis type 1...

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Bibliographic Details
Main Authors: A. M. Pivovarova, M. Yu. Dorofeeva, A. R. Zabrodina, S. V. Bochenkov, A. V. Grigoryeva, Z. K. Gorchkhanova, V. R. Voronina
Format: Article
Language:Russian
Published: ABV-press 2024-07-01
Series:Русский журнал детской неврологии
Subjects:
neurofibromatosis type 1
plexiform neurofibromas
selumetinib
adverse events
toxicity control
prevention of complications
Online Access:https://rjdn.abvpress.ru/jour/article/view/471
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