Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential
Portulaca oleracea L. (purslane) is a spontaneous herb whose shoots are appreciated in the Mediterranean and Asian diets for their fresh flavor and crunchy texture. In addition to PUFA (PolyUnsaturated Fatty Acids), it contains unusual polyphenolic alkaloids called oleraceins. This work aimed at inv...
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Elsevier
2025-01-01
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| Series: | Current Research in Food Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2665927125000231 |
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| author | Ciro Cannavacciuolo Assunta Napolitano Verena M. Dirsch Elke H. Heiss Milena Masullo Sonia Piacente |
| author_facet | Ciro Cannavacciuolo Assunta Napolitano Verena M. Dirsch Elke H. Heiss Milena Masullo Sonia Piacente |
| author_sort | Ciro Cannavacciuolo |
| collection | DOAJ |
| description | Portulaca oleracea L. (purslane) is a spontaneous herb whose shoots are appreciated in the Mediterranean and Asian diets for their fresh flavor and crunchy texture. In addition to PUFA (PolyUnsaturated Fatty Acids), it contains unusual polyphenolic alkaloids called oleraceins. This work aimed at investigating the oleracein profile of different ‘green’ extracts of the leaves of Portulaca oleracea and evaluating their antioxidant capacity. An LC-MS screening of different extracts revealed the infusion as the extract richest in oleraceins. Qualitative and quantitative analysis of oleraceins in this extract resulted in the identification of three polyphenolic alkaloids never reported before and in the definition of oleracein A as the most abundant alkaloid. An oleracein-enriched fraction from the infusion and its hydrolysed derivative exhibited radical scavenging activity in vitro and led to activation of the Nrf2 pathway in cells without apparent cytotoxicity. Thus, its oleracein content may make purslane a potential nutraceutical for alleviating redox distress. |
| format | Article |
| id | doaj-art-b4e5df1b801c406fab528e6324c7bebe |
| institution | Kabale University |
| issn | 2665-9271 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Current Research in Food Science |
| spelling | doaj-art-b4e5df1b801c406fab528e6324c7bebe2025-02-06T05:12:46ZengElsevierCurrent Research in Food Science2665-92712025-01-0110100992Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potentialCiro Cannavacciuolo0Assunta Napolitano1Verena M. Dirsch2Elke H. Heiss3Milena Masullo4Sonia Piacente5Dipartimento di Farmacia, Università Degli Studi di Salerno, Via Giovanni Paolo II n. 132, 84084, Fisciano, SA, Italy; PhD Program in Drug Discovery and Development, Università Degli Studi di Salerno, Via Giovanni Paolo II n. 132, I-84084, Fisciano, SA, ItalyDipartimento di Farmacia, Università Degli Studi di Salerno, Via Giovanni Paolo II n. 132, 84084, Fisciano, SA, ItalyDepartment of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090, Vienna, AustriaDepartment of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090, Vienna, AustriaDipartimento di Farmacia, Università Degli Studi di Salerno, Via Giovanni Paolo II n. 132, 84084, Fisciano, SA, ItalyDipartimento di Farmacia, Università Degli Studi di Salerno, Via Giovanni Paolo II n. 132, 84084, Fisciano, SA, Italy; National Biodiversity Future Center (NBFC), 90133, Palermo, Italy; Corresponding author. Dipartimento di Farmacia, Università degli Studi di Salerno, Via Giovanni Paolo II n. 132, 84084, Fisciano, SA, Italy.Portulaca oleracea L. (purslane) is a spontaneous herb whose shoots are appreciated in the Mediterranean and Asian diets for their fresh flavor and crunchy texture. In addition to PUFA (PolyUnsaturated Fatty Acids), it contains unusual polyphenolic alkaloids called oleraceins. This work aimed at investigating the oleracein profile of different ‘green’ extracts of the leaves of Portulaca oleracea and evaluating their antioxidant capacity. An LC-MS screening of different extracts revealed the infusion as the extract richest in oleraceins. Qualitative and quantitative analysis of oleraceins in this extract resulted in the identification of three polyphenolic alkaloids never reported before and in the definition of oleracein A as the most abundant alkaloid. An oleracein-enriched fraction from the infusion and its hydrolysed derivative exhibited radical scavenging activity in vitro and led to activation of the Nrf2 pathway in cells without apparent cytotoxicity. Thus, its oleracein content may make purslane a potential nutraceutical for alleviating redox distress.http://www.sciencedirect.com/science/article/pii/S2665927125000231Portulaca oleracea L.Purslane‘Green’ extractsOleraceinsCyclo-DOPA phenolic alkaloidsAntioxidant activity |
| spellingShingle | Ciro Cannavacciuolo Assunta Napolitano Verena M. Dirsch Elke H. Heiss Milena Masullo Sonia Piacente Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential Current Research in Food Science Portulaca oleracea L. Purslane ‘Green’ extracts Oleraceins Cyclo-DOPA phenolic alkaloids Antioxidant activity |
| title | Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential |
| title_full | Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential |
| title_fullStr | Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential |
| title_full_unstemmed | Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential |
| title_short | Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential |
| title_sort | oleraceins from portulaca oleracea leaves quali quantitative determination and antioxidant potential |
| topic | Portulaca oleracea L. Purslane ‘Green’ extracts Oleraceins Cyclo-DOPA phenolic alkaloids Antioxidant activity |
| url | http://www.sciencedirect.com/science/article/pii/S2665927125000231 |
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