ASIC1a-Dependent Potentiation of Acid-Sensing Ion Channel Currents by Cyanide

ASIC1a-Dependent Potentiation of Acid-Sensing Ion Channel Currents by Cyanide

Cyanide (CN) is a potent, fast-acting toxicant that impacts endogenous biomolecules in the nervous system, including acid-sensing ion channels (ASICs), which play a vital role in various neurological and psychological conditions. Here, we demonstrate that CN rapidly potentiates ASIC currents in cult...

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Bibliographic Details
Main Authors: Qian Jiang, Felix Yang, Amber Sun, Yuyang Chu, Joseph Cascone, Dylan Glaser, Xiang-Ping Chu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomolecules
Subjects:
acid-sensing ion channels
cyanide
zinc
point mutation
patch-clamp recording
cultured cortical neuron
Online Access:https://www.mdpi.com/2218-273X/15/4/479
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