Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia model

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Main Authors: Deborah E. Daniels, Joeseph Hawksworth, Sara El Hoss, Fatima O. Oyawoye, Ivan Ferrer-Vicens, Marieangela C. Wilson, Jan Frayne
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-04-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12023
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author Deborah E. Daniels
Joeseph Hawksworth
Sara El Hoss
Fatima O. Oyawoye
Ivan Ferrer-Vicens
Marieangela C. Wilson
Jan Frayne
author_facet Deborah E. Daniels
Joeseph Hawksworth
Sara El Hoss
Fatima O. Oyawoye
Ivan Ferrer-Vicens
Marieangela C. Wilson
Jan Frayne
author_sort Deborah E. Daniels
collection DOAJ
description Not available.
format Article
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institution OA Journals
issn 0390-6078
1592-8721
language English
publishDate 2025-04-01
publisher Ferrata Storti Foundation
record_format Article
series Haematologica
spelling doaj-art-b4e0706487ae4e94a67996ff555be6412025-08-20T02:09:23ZengFerrata Storti FoundationHaematologica0390-60781592-87212025-04-01999110.3324/haematol.2024.287221Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia modelDeborah E. Daniels0Joeseph Hawksworth1Sara El Hoss2Fatima O. Oyawoye3Ivan Ferrer-Vicens4Marieangela C. Wilson5Jan Frayne6School of Biochemistry, University of Bristol, BristolSchool of Biochemistry, University of Bristol, BristolRed Cell Haematology Lab, Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Sciences, King’s College London, United Kingdom; Laboratory of Molecular Mechanisms of Hematological Disorders and Therapeutic Implications, Institut IMAGINE, INSERM UMR1163, ParisSchool of Biochemistry, University of Bristol, BristolSchool of Biochemistry, University of Bristol, BristolProteomics Facility, Faculty of Life Sciences, University of Bristol, BristolSchool of Biochemistry, University of Bristol, Bristol Not available. https://haematologica.org/article/view/12023
spellingShingle Deborah E. Daniels
Joeseph Hawksworth
Sara El Hoss
Fatima O. Oyawoye
Ivan Ferrer-Vicens
Marieangela C. Wilson
Jan Frayne
Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia model
Haematologica
title Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia model
title_full Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia model
title_fullStr Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia model
title_full_unstemmed Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia model
title_short Optimizing CRISPR methodology for precise gene editing in the erythroid cell line BEL-A with high efficiency generation of a sickle cell anemia model
title_sort optimizing crispr methodology for precise gene editing in the erythroid cell line bel a with high efficiency generation of a sickle cell anemia model
url https://haematologica.org/article/view/12023
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