A genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin.

Anchorage-independent proliferation is a hallmark of oncogenic transformation and is thought to be conducive to proliferation of cancer cells away from their site of origin. We have previously reported that primary Schwann cells expressing the SV40 Large T antigen (LT) are not fully transformed in t...

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Bibliographic Details
Main Authors: Davide Danovi, Catherine A Cremona, Gisela Machado-da-Silva, Sreya Basu, Luke A Noon, Simona Parrinello, Alison C Lloyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011774&type=printable
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