Dexamethasone-induced whitening of rabbit brown adipose tissue: leptin resistance and mitochondrial dysfunction

Dexamethasone-induced whitening of rabbit brown adipose tissue: leptin resistance and mitochondrial dysfunction

Abstract Background Research on the effects of exogenous glucocorticoids on brown adipose tissue (BAT) is crucial for understanding how these hormones can induce metabolic disorders such as obesity. In this study, we explored the effects of glucocorticoids, specifically dexamethasone (Dex), on the m...

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Bibliographic Details
Main Authors: Xiaoqin Tang, Beibei Zhang, Puhang Xie, Yanpei Wei, Yanbo Qiu, Xiaohua Yi, Ziru Zhang, Muzi She, Xiuzhu Sun, Shuhui Wang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Genomics
Subjects:
Dexamethasone
Brown adipose tissue whitening
Mitochondrial dysfunction
Online Access:https://doi.org/10.1186/s12864-025-11502-3
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