Immunogenicity and safety of live attenuated and recombinant/inactivated varicella zoster vaccines in people living with HIV: A systematic review
Few papers focus their attention on VZV vaccination effectiveness among people living with HIV (PLWH). Flanking the live attenuated vaccine (VZL) available, a newly recombinant vaccine (RZV) was recently introduced and approved for HZ prevention among adults. PLWH represents a population on which a...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/21645515.2024.2341456 |
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| author | Valentina Carta Lucia Mangeri Giorgio Tiecco Emanuele Focà Eugenia Quiros-Roldan Maria Antonia De Francesco |
| author_facet | Valentina Carta Lucia Mangeri Giorgio Tiecco Emanuele Focà Eugenia Quiros-Roldan Maria Antonia De Francesco |
| author_sort | Valentina Carta |
| collection | DOAJ |
| description | Few papers focus their attention on VZV vaccination effectiveness among people living with HIV (PLWH). Flanking the live attenuated vaccine (VZL) available, a newly recombinant vaccine (RZV) was recently introduced and approved for HZ prevention among adults. PLWH represents a population on which a particular attention should be applied, in order to guarantee the vaccine efficacy and safety. We performed a literature search in USNLM, PubMed, PubMed Central, PMC and Cochrane Library. From all the publications found eligible, data were extracted and processed per population, vaccine type, immunogenicity and ADRs. The review of the 13 included studies shows that both RZV and VZL are immunogenic and have an acceptable safety profile in adults and children living with HIV. However, given the lack of research available about vaccine efficacy in preventing VZV and HZ in PLWH, additional studies need to be performed, in order to achieve a full completeness of data. |
| format | Article |
| id | doaj-art-b4d1786bf6274d5baefb11f86ac082b7 |
| institution | OA Journals |
| issn | 2164-5515 2164-554X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj-art-b4d1786bf6274d5baefb11f86ac082b72025-08-20T02:34:25ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2024-12-0120110.1080/21645515.2024.2341456Immunogenicity and safety of live attenuated and recombinant/inactivated varicella zoster vaccines in people living with HIV: A systematic reviewValentina Carta0Lucia Mangeri1Giorgio Tiecco2Emanuele Focà3Eugenia Quiros-Roldan4Maria Antonia De Francesco5Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia-Romagna, Brescia, ItalyIstituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia-Romagna, Brescia, ItalyDepartment of Clinical and Experimental Sciences, University of Brescia-ASST Spedali Civili, Brescia, ItalyDepartment of Clinical and Experimental Sciences, University of Brescia-ASST Spedali Civili, Brescia, ItalyDepartment of Clinical and Experimental Sciences, University of Brescia-ASST Spedali Civili, Brescia, ItalyDepartment of Molecular and Translational Medicine, Institute of Microbiology, University of Brescia-ASST Spedali Civili, Brescia, ItalyFew papers focus their attention on VZV vaccination effectiveness among people living with HIV (PLWH). Flanking the live attenuated vaccine (VZL) available, a newly recombinant vaccine (RZV) was recently introduced and approved for HZ prevention among adults. PLWH represents a population on which a particular attention should be applied, in order to guarantee the vaccine efficacy and safety. We performed a literature search in USNLM, PubMed, PubMed Central, PMC and Cochrane Library. From all the publications found eligible, data were extracted and processed per population, vaccine type, immunogenicity and ADRs. The review of the 13 included studies shows that both RZV and VZL are immunogenic and have an acceptable safety profile in adults and children living with HIV. However, given the lack of research available about vaccine efficacy in preventing VZV and HZ in PLWH, additional studies need to be performed, in order to achieve a full completeness of data.https://www.tandfonline.com/doi/10.1080/21645515.2024.2341456Vaccinesafetyimmunogenicityherpes zostervaricella |
| spellingShingle | Valentina Carta Lucia Mangeri Giorgio Tiecco Emanuele Focà Eugenia Quiros-Roldan Maria Antonia De Francesco Immunogenicity and safety of live attenuated and recombinant/inactivated varicella zoster vaccines in people living with HIV: A systematic review Human Vaccines & Immunotherapeutics Vaccine safety immunogenicity herpes zoster varicella |
| title | Immunogenicity and safety of live attenuated and recombinant/inactivated varicella zoster vaccines in people living with HIV: A systematic review |
| title_full | Immunogenicity and safety of live attenuated and recombinant/inactivated varicella zoster vaccines in people living with HIV: A systematic review |
| title_fullStr | Immunogenicity and safety of live attenuated and recombinant/inactivated varicella zoster vaccines in people living with HIV: A systematic review |
| title_full_unstemmed | Immunogenicity and safety of live attenuated and recombinant/inactivated varicella zoster vaccines in people living with HIV: A systematic review |
| title_short | Immunogenicity and safety of live attenuated and recombinant/inactivated varicella zoster vaccines in people living with HIV: A systematic review |
| title_sort | immunogenicity and safety of live attenuated and recombinant inactivated varicella zoster vaccines in people living with hiv a systematic review |
| topic | Vaccine safety immunogenicity herpes zoster varicella |
| url | https://www.tandfonline.com/doi/10.1080/21645515.2024.2341456 |
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