Reaction time and mortality from the major causes of death: the NHANES-III study.
<h4>Objective</h4>Studies examining the relation of information processing speed, as measured by reaction time, with mortality are scarce. We explored these associations in a representative sample of the US population.<h4>Methods</h4>Participants were 5,134 adults (2,342 men)...
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0082959&type=printable |
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| author | Gareth Hagger-Johnson Ian J Deary Carolyn A Davies Alexander Weiss G David Batty |
| author_facet | Gareth Hagger-Johnson Ian J Deary Carolyn A Davies Alexander Weiss G David Batty |
| author_sort | Gareth Hagger-Johnson |
| collection | DOAJ |
| description | <h4>Objective</h4>Studies examining the relation of information processing speed, as measured by reaction time, with mortality are scarce. We explored these associations in a representative sample of the US population.<h4>Methods</h4>Participants were 5,134 adults (2,342 men) aged 20-59 years from the Third National Health and Nutrition Examination Survey (NHANES III, 1988-94).<h4>Results</h4>Adjusted for age, sex, and ethnic minority status, a 1 SD slower reaction time was associated with a raised risk of mortality from all-causes (HR = 1.25, 95% CI 1.12, 1.39) and cardiovascular disease (CVD) (HR = 1.36, 95% CI 1.17, 1.58). Having 1 SD more variable reaction time was also associated with greater risk of all-cause (HR = 1.36, 95% CI 1.19, 1.55) and CVD (HR = 1.50, 95% CI 1.33, 1.70) mortality. No associations were observed for cancer mortality. The magnitude of the relationships was comparable in size to established risk factors in this dataset, such as smoking.<h4>Interpretation</h4>Alongside better-established risk factors, reaction time is associated with increased risk of premature death and cardiovascular disease. It is a candidate risk factor for all-cause and cause-specific mortality. |
| format | Article |
| id | doaj-art-b4bd5d44ce8a4ce286ac2ac4bd09e698 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
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| spelling | doaj-art-b4bd5d44ce8a4ce286ac2ac4bd09e6982025-08-20T02:34:14ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0191e8295910.1371/journal.pone.0082959Reaction time and mortality from the major causes of death: the NHANES-III study.Gareth Hagger-JohnsonIan J DearyCarolyn A DaviesAlexander WeissG David Batty<h4>Objective</h4>Studies examining the relation of information processing speed, as measured by reaction time, with mortality are scarce. We explored these associations in a representative sample of the US population.<h4>Methods</h4>Participants were 5,134 adults (2,342 men) aged 20-59 years from the Third National Health and Nutrition Examination Survey (NHANES III, 1988-94).<h4>Results</h4>Adjusted for age, sex, and ethnic minority status, a 1 SD slower reaction time was associated with a raised risk of mortality from all-causes (HR = 1.25, 95% CI 1.12, 1.39) and cardiovascular disease (CVD) (HR = 1.36, 95% CI 1.17, 1.58). Having 1 SD more variable reaction time was also associated with greater risk of all-cause (HR = 1.36, 95% CI 1.19, 1.55) and CVD (HR = 1.50, 95% CI 1.33, 1.70) mortality. No associations were observed for cancer mortality. The magnitude of the relationships was comparable in size to established risk factors in this dataset, such as smoking.<h4>Interpretation</h4>Alongside better-established risk factors, reaction time is associated with increased risk of premature death and cardiovascular disease. It is a candidate risk factor for all-cause and cause-specific mortality.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0082959&type=printable |
| spellingShingle | Gareth Hagger-Johnson Ian J Deary Carolyn A Davies Alexander Weiss G David Batty Reaction time and mortality from the major causes of death: the NHANES-III study. PLoS ONE |
| title | Reaction time and mortality from the major causes of death: the NHANES-III study. |
| title_full | Reaction time and mortality from the major causes of death: the NHANES-III study. |
| title_fullStr | Reaction time and mortality from the major causes of death: the NHANES-III study. |
| title_full_unstemmed | Reaction time and mortality from the major causes of death: the NHANES-III study. |
| title_short | Reaction time and mortality from the major causes of death: the NHANES-III study. |
| title_sort | reaction time and mortality from the major causes of death the nhanes iii study |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0082959&type=printable |
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