Diagnosis of bovine rotavirus: an overview of currently available methods

Bovine rotavirus (BRV) is a significant pathogen that causes diarrhea in calves, profoundly impacting the cattle industry and resulting in substantial economic losses. Currently, the established diagnostic approaches for BRV primarily include etiological methods, such as electron microscopy, virus i...

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Main Authors: Ying Huang, Zhi Li, Yong Fu, Shu Qin Wang, Ming Kang, Ru Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1550601/full
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author Ying Huang
Zhi Li
Yong Fu
Shu Qin Wang
Ming Kang
Ru Meng
author_facet Ying Huang
Zhi Li
Yong Fu
Shu Qin Wang
Ming Kang
Ru Meng
author_sort Ying Huang
collection DOAJ
description Bovine rotavirus (BRV) is a significant pathogen that causes diarrhea in calves, profoundly impacting the cattle industry and resulting in substantial economic losses. Currently, the established diagnostic approaches for BRV primarily include etiological methods, such as electron microscopy, virus isolation, and culture; serological methods, including enzyme-linked immunosorbent assay (ELISA), latex agglutination test (LAT), and immunofluorescence techniques; and molecular biological methods, such as reverse transcription-polymerase chain reaction (RT-PCR), real-time quantitative PCR (qPCR), and loop-mediated isothermal amplification (LAMP), as well as next-generation sequencing (NGS) technology. This review summarizes the current diagnostic methods for BRV, discusses their advantages and disadvantages, and presents future perspectives on BRV diagnosis, aiming to provide valuable references for the effective diagnosis and control of BRV-related diseases.
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publisher Frontiers Media S.A.
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series Frontiers in Microbiology
spelling doaj-art-b4bb8de1adca49edb521dbfa8457f4022025-08-20T02:45:53ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2025-02-011610.3389/fmicb.2025.15506011550601Diagnosis of bovine rotavirus: an overview of currently available methodsYing Huang0Zhi Li1Yong Fu2Shu Qin Wang3Ming Kang4Ru Meng5Department of Veterinary Medicine, Qinghai University, Xining, ChinaQinghai Academy of Animal Sciences and Veterinary Medicine, Qinghai University, Xining, ChinaQinghai Academy of Animal Sciences and Veterinary Medicine, Qinghai University, Xining, ChinaXining Animal Disease Control Center, Xining, ChinaDepartment of Veterinary Medicine, Qinghai University, Xining, ChinaXining Animal Disease Control Center, Xining, ChinaBovine rotavirus (BRV) is a significant pathogen that causes diarrhea in calves, profoundly impacting the cattle industry and resulting in substantial economic losses. Currently, the established diagnostic approaches for BRV primarily include etiological methods, such as electron microscopy, virus isolation, and culture; serological methods, including enzyme-linked immunosorbent assay (ELISA), latex agglutination test (LAT), and immunofluorescence techniques; and molecular biological methods, such as reverse transcription-polymerase chain reaction (RT-PCR), real-time quantitative PCR (qPCR), and loop-mediated isothermal amplification (LAMP), as well as next-generation sequencing (NGS) technology. This review summarizes the current diagnostic methods for BRV, discusses their advantages and disadvantages, and presents future perspectives on BRV diagnosis, aiming to provide valuable references for the effective diagnosis and control of BRV-related diseases.https://www.frontiersin.org/articles/10.3389/fmicb.2025.1550601/fullbovine rotavirusdiagnosisetiological methodsserological methodsmolecular biological methods
spellingShingle Ying Huang
Zhi Li
Yong Fu
Shu Qin Wang
Ming Kang
Ru Meng
Diagnosis of bovine rotavirus: an overview of currently available methods
Frontiers in Microbiology
bovine rotavirus
diagnosis
etiological methods
serological methods
molecular biological methods
title Diagnosis of bovine rotavirus: an overview of currently available methods
title_full Diagnosis of bovine rotavirus: an overview of currently available methods
title_fullStr Diagnosis of bovine rotavirus: an overview of currently available methods
title_full_unstemmed Diagnosis of bovine rotavirus: an overview of currently available methods
title_short Diagnosis of bovine rotavirus: an overview of currently available methods
title_sort diagnosis of bovine rotavirus an overview of currently available methods
topic bovine rotavirus
diagnosis
etiological methods
serological methods
molecular biological methods
url https://www.frontiersin.org/articles/10.3389/fmicb.2025.1550601/full
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