Current understanding of eryptosis: mechanisms, physiological functions, role in disease, pharmacological applications, and nomenclature recommendations

Current understanding of eryptosis: mechanisms, physiological functions, role in disease, pharmacological applications, and nomenclature recommendations

Abstract Early studies have shown that erythrocytes have caspase-3 and caspase-8 and are capable of dying through an apoptotic-like cell death triggered by Ca2+ ionophores. This cell death is associated with apoptosis-like morphological signs, including cell shrinkage, membrane blebbing, and phospha...

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Main Authors: Anton Tkachenko, Mohammad A. Alfhili, Jawaher Alsughayyir, Alessandro Attanzio, Abdulla Al Mamun Bhuyan, Bożena Bukowska, Antonio Cilla, Martha A. Quintanar-Escorza, Michael Föller, Ondrej Havranek, Kashif Jilani, Anatolii Onishchenko, Etheresia Pretorius, Volodymyr Prokopiuk, Ignazio Restivo, Luisa Tesoriere, Grazia Maria Virzì, Thomas Wieder
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07784-w
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