The mediating effect of frailty between social isolation and cognitive function in elderly patients with type 2 diabetes
[Objective] To analyze the mediating effect of frailty between social isolation and cognitive function in elderly patients with type 2 diabetes mellitus. [Methods] A total of 300 elderly patients with type 2 diabetes mellitus admitted to the inpatient department of the Department of Geriatric Endocr...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of International Journal of Geriatrics
2025-07-01
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| Series: | Guoji laonian yixue zazhi |
| Subjects: | |
| Online Access: | http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.04.005&lang=en |
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| Summary: | [Objective] To analyze the mediating effect of frailty between social isolation and cognitive function in elderly patients with type 2 diabetes mellitus. [Methods] A total of 300 elderly patients with type 2 diabetes mellitus admitted to the inpatient department of the Department of Geriatric Endocrinology of the First Affiliated Hospital of Guangxi Medical University from October 2023 to February 2024 were selected by convenience sampling. A general information questionnaire, the Social Network Scale Short Form, the Tilburg Frailty Scale, and the Chinese version of the Simple Intelligent Mental State Examination Scale were used to investigate, and the mediating effect were analyzed using the Process plug-in in SPSS26.0 software. [Results] 300 elderly patients with type 2 diabetes mellitus scored 14 (9, 20) points for social isolation and 103 (34.33%) for social isolation; 5 (3, 7) points for frailty and 169 (56.33%) for frailty; 25 (23, 27) points for cognitive function and 98 (32.67%) for cognitive impairment.The frailty score was negatively correlated with the social isolation score (r=-0.327, P<0.001), the frailty score was negatively correlated with the cognitive function score (r=-0.394, P<0.001), and the social isolation was positively correlated with the cognitive function score (r=0.370,P<0.001).Bootstrap test showed that the indirect effect value was 0.071 (95%CI: 0.038-0.116), indicating that the indirect effect was established; the direct effect was 0.148 (95%CI: 0.088-0.208), indicating that weakness played a partial mediating role between social isolation and cognitive function, and the indirect effect (0.071) accounted for 32.42% of the total effect (0.219). [Conclusion] Social isolation, frailty and cognitive impairment in elderly patients with type 2 diabetes type 2 diabetes mellitus are at a high level, and frailty has a partial mediating effect between social isolation and cognitive function in elderly patients with type 2 diabetes mellitus, suggesting that social isolation can not only directly affect cognitive function, but also indirectly affect cognitive function through frailty. |
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| ISSN: | 1674-7593 |