Comprehensive evaluation of methods for identifying tissues or cell types of origin of the plasma cell-free transcriptome

Comprehensive evaluation of methods for identifying tissues or cell types of origin of the plasma cell-free transcriptome

Plasma cell-free RNA (cfRNA) is derived from cells in various tissues and organs throughout the body and reflects the physiological and pathological conditions. Identifying the origins of cfRNA is essential for comprehending its variations. Only a few tools are designed for cfRNA deconvolution, and...

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Bibliographic Details
Main Authors: Tingyu Yang, Yulong Qin, Shuo Yan, Sijia Guo, Jinghua Sun, Jiayi Huang, Jiayi Li, Qing Zhou, Xin Jin, Wen-Jing Wang
Format: Article
Language:English
Published: PeerJ Inc. 2025-04-01
Series:PeerJ
Subjects:
Plasma cfRNA
Cell origins
Tissue origins
Cancer classification
Online Access:https://peerj.com/articles/19241.pdf
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https://peerj.com/articles/19241.pdf

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