Computational discovery of plant-derived flavonoids as potential amyloid-β fibril disaggregating agents for alzheimer’s disease

The neurological hallmark of Alzheimer's disease (AD) is a pathogenic deposition of amyloid-β peptide in the brain. Amyloid-β aggregation is neurotoxic and ultimately results in dysfunction of the nervous system. The present study aims to find potential amyloid-β fibrils disaggregating molecule...

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Main Authors: Uthirapathi Logeswari Rakesh, Golla Anil Kumar, Theivendren Panneerselvam, Parasuraman Pavadai, Suganthan Veerachamy, Ponnusamy Palanisamy, SunilKumar Bandral, Selvaraj Kunjiappan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Brain Disorders
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666459325000538
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