Which patients on a gynecologic oncology service will require perioperative transfusion? A single-center retrospective cohort study

The purpose of this study was to determine which patient- or surgery-related factors are predictive of need for perioperative transfusion to avoid obtaining unnecessary pre-operative type and screens (T&S). We conducted an observational retrospective cohort study of 1200 women ≥ 18 years old und...

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Main Authors: Gregory W. Kirschen, Samantha M. Dayton, Sophia Blakey-Cheung, Michael L. Pearl
Format: Article
Language:English
Published: IMR Press 2021-02-01
Series:Clinical and Experimental Obstetrics & Gynecology
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Online Access:https://www.imrpress.com/journal/CEOG/48/1/10.31083/j.ceog.2021.01.2152
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author Gregory W. Kirschen
Samantha M. Dayton
Sophia Blakey-Cheung
Michael L. Pearl
author_facet Gregory W. Kirschen
Samantha M. Dayton
Sophia Blakey-Cheung
Michael L. Pearl
author_sort Gregory W. Kirschen
collection DOAJ
description The purpose of this study was to determine which patient- or surgery-related factors are predictive of need for perioperative transfusion to avoid obtaining unnecessary pre-operative type and screens (T&S). We conducted an observational retrospective cohort study of 1200 women ≥ 18 years old undergoing gynecologic surgery for benign, possibly benign, or malignant indications on a gynecologic oncology service at a university medical center from 2009-2016. A logistic regression model was used to examine patient-related and surgery-related variables predictive of outcome of transfusion. Independent variables included patient demographics, comorbidities, and surgical indication surgical route, and surgical type. Dependent variable was transfusion outcome (T&S only, conversion to type and cross (T&C), or transfusion). Eight hundred ninety-nine (74.9%) women underwent pre-operative T&S, of which 118 (9.8%) were converted to T&C, and 80 (6.7%) received a transfusion of blood or blood products. Cancer indication, major surgery, and preoperative hematocrit less than 36% were significantly associated with need for transfusion (P = 0.002, P < 0.0001, P < 0.0001, respectively). Patients with a benign indication undergoing minor procedures and with normal preoperative hematocrit are least likely to require transfusion.
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spelling doaj-art-b49b8585dfe04f7f88c7f88b40fd665e2025-08-20T03:48:35ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-02-01481475210.31083/j.ceog.2021.01.2152S0390-6663(21)00043-9Which patients on a gynecologic oncology service will require perioperative transfusion? A single-center retrospective cohort studyGregory W. Kirschen0Samantha M. Dayton1Sophia Blakey-Cheung2Michael L. Pearl3Department of Gynecology and Obstetrics, Johns Hopkins Medicine, MD 21287 Baltimore, United StatesDepartment of Obstetrics, Gynecology & Reproductive Medicine, Stony Brook University Hospital, Stony Brook, 11794 NY, United StatesDepartment of Obstetrics and Gynecology, Northwell Health System, Southside Hospital, 11706 NY, United StatesDepartment of Obstetrics, Gynecology & Reproductive Medicine, Stony Brook University Hospital, Stony Brook, 11794 NY, United StatesThe purpose of this study was to determine which patient- or surgery-related factors are predictive of need for perioperative transfusion to avoid obtaining unnecessary pre-operative type and screens (T&S). We conducted an observational retrospective cohort study of 1200 women ≥ 18 years old undergoing gynecologic surgery for benign, possibly benign, or malignant indications on a gynecologic oncology service at a university medical center from 2009-2016. A logistic regression model was used to examine patient-related and surgery-related variables predictive of outcome of transfusion. Independent variables included patient demographics, comorbidities, and surgical indication surgical route, and surgical type. Dependent variable was transfusion outcome (T&S only, conversion to type and cross (T&C), or transfusion). Eight hundred ninety-nine (74.9%) women underwent pre-operative T&S, of which 118 (9.8%) were converted to T&C, and 80 (6.7%) received a transfusion of blood or blood products. Cancer indication, major surgery, and preoperative hematocrit less than 36% were significantly associated with need for transfusion (P = 0.002, P < 0.0001, P < 0.0001, respectively). Patients with a benign indication undergoing minor procedures and with normal preoperative hematocrit are least likely to require transfusion.https://www.imrpress.com/journal/CEOG/48/1/10.31083/j.ceog.2021.01.2152blood losshemorrhageminimally-invasive surgerycost savingsevidence-based practice
spellingShingle Gregory W. Kirschen
Samantha M. Dayton
Sophia Blakey-Cheung
Michael L. Pearl
Which patients on a gynecologic oncology service will require perioperative transfusion? A single-center retrospective cohort study
Clinical and Experimental Obstetrics & Gynecology
blood loss
hemorrhage
minimally-invasive surgery
cost savings
evidence-based practice
title Which patients on a gynecologic oncology service will require perioperative transfusion? A single-center retrospective cohort study
title_full Which patients on a gynecologic oncology service will require perioperative transfusion? A single-center retrospective cohort study
title_fullStr Which patients on a gynecologic oncology service will require perioperative transfusion? A single-center retrospective cohort study
title_full_unstemmed Which patients on a gynecologic oncology service will require perioperative transfusion? A single-center retrospective cohort study
title_short Which patients on a gynecologic oncology service will require perioperative transfusion? A single-center retrospective cohort study
title_sort which patients on a gynecologic oncology service will require perioperative transfusion a single center retrospective cohort study
topic blood loss
hemorrhage
minimally-invasive surgery
cost savings
evidence-based practice
url https://www.imrpress.com/journal/CEOG/48/1/10.31083/j.ceog.2021.01.2152
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