CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm
Accumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury. Recent publications addressing therapy of cytokine storms recommended new extracorporeal therapies such as hemoadsorption. This case report...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2021/9937499 |
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| _version_ | 1832557048178409472 |
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| author | Alice-Christin Acevedo Michael Zoller Christina Scharf Uwe Liebchen Michael Irlbeck Ines Schroeder |
| author_facet | Alice-Christin Acevedo Michael Zoller Christina Scharf Uwe Liebchen Michael Irlbeck Ines Schroeder |
| author_sort | Alice-Christin Acevedo |
| collection | DOAJ |
| description | Accumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury. Recent publications addressing therapy of cytokine storms recommended new extracorporeal therapies such as hemoadsorption. This case report describes a 59-year-old SARS-CoV-2-positive patient with severe ARDS. Due to severe hyperinflammation with concomitant hemodynamic instability and progressive renal failure, combination of continuous renal replacement and CytoSorb® hemoadsorption therapy was initiated. Treatment resulted immediately in a control of the hyperinflammatory response. Simultaneously, lung function continued to improve accompanied by profound hemodynamic stabilization. We report the successful utilization of CytoSorb® hemoadsorption in the treatment of a patient with SARS-CoV-2-induced cytokine storm syndrome. |
| format | Article |
| id | doaj-art-b4902a290cc04262a2d62cedf4f0ed33 |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-b4902a290cc04262a2d62cedf4f0ed332025-02-03T05:43:47ZengWileyCase Reports in Critical Care2090-64202090-64392021-01-01202110.1155/2021/99374999937499CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine StormAlice-Christin Acevedo0Michael Zoller1Christina Scharf2Uwe Liebchen3Michael Irlbeck4Ines Schroeder5Department of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, GermanyDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, GermanyDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, GermanyDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, GermanyDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, GermanyDepartment of Anesthesiology, LMU Hospital, Ludwig Maximilians University, Munich, GermanyAccumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury. Recent publications addressing therapy of cytokine storms recommended new extracorporeal therapies such as hemoadsorption. This case report describes a 59-year-old SARS-CoV-2-positive patient with severe ARDS. Due to severe hyperinflammation with concomitant hemodynamic instability and progressive renal failure, combination of continuous renal replacement and CytoSorb® hemoadsorption therapy was initiated. Treatment resulted immediately in a control of the hyperinflammatory response. Simultaneously, lung function continued to improve accompanied by profound hemodynamic stabilization. We report the successful utilization of CytoSorb® hemoadsorption in the treatment of a patient with SARS-CoV-2-induced cytokine storm syndrome.http://dx.doi.org/10.1155/2021/9937499 |
| spellingShingle | Alice-Christin Acevedo Michael Zoller Christina Scharf Uwe Liebchen Michael Irlbeck Ines Schroeder CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm Case Reports in Critical Care |
| title | CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm |
| title_full | CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm |
| title_fullStr | CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm |
| title_full_unstemmed | CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm |
| title_short | CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm |
| title_sort | cytosorb r hemoadsorption as a promising tool to handle covid 19 induced cytokine storm |
| url | http://dx.doi.org/10.1155/2021/9937499 |
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