Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.

Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.

Mouse Embryonic Stem (ES) cells express a unique set of microRNAs (miRNAs), the miR-290-295 cluster. To elucidate the role of these miRNAs and how they integrate into the ES cell regulatory network requires identification of their direct regulatory targets. The difficulty, however, arises from the l...

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Bibliographic Details
Main Authors: Sophie A Hanina, William Mifsud, Thomas A Down, Katsuhiko Hayashi, Dónal O'Carroll, Kaiqin Lao, Eric A Miska, M Azim Surani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001163&type=printable
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