Immune Checkpoint Inhibitors in Frail Older Patients: A Review of Current Evidence

Immune Checkpoint Inhibitors in Frail Older Patients: A Review of Current Evidence

Age-related physiological changes, such as impaired organ function (i.e., renal, cardiac), frailty, reduced bone marrow reserves and altered pharmacokinetics, complicate treatment decisions and compromise survival in older patients with cancer. Immune checkpoint inhibitors (ICIs) have transformed th...

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Main Authors: Marcus Vetter, Vérène Dougoud-Chauvin, Laure Poudens Gaudout, Anita Margulies, Jan Gärtner, Till Wallrabenstein, Nina Rosa Neuendorff, Claudia Bollinger, Michael Gagesch, Mathias Schlögl
Format: Article
Language:English
Published: THE HEALTHBOOK COMPANY LTD. 2024-12-01
Series:healthbook TIMES. Oncology Hematology
Online Access:https://doi.org/10.36000/HBT.OH.2024.22.165
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