Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy
Neurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Signif...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2008-12-01
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| Series: | Бюллетень сибирской медицины |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/3446 |
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| author | N. B. Gubanova Yu. V. Karakulova |
| author_facet | N. B. Gubanova Yu. V. Karakulova |
| author_sort | N. B. Gubanova |
| collection | DOAJ |
| description | Neurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Significant decreasing of blood serotonin level in patients with during the interictal period which decreased more after the generalised convulsive and myoclonic seasures was found by the immune assay method. |
| format | Article |
| id | doaj-art-b471bb559ea74906848cf9fc03a16e42 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2008-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-b471bb559ea74906848cf9fc03a16e422025-08-20T04:00:19ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842008-12-0175-1878910.20538/1682-0363-2008-5-1-87-892093Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsyN. B. Gubanova0Yu. V. Karakulova1Пермская государственная медицинская академияПермская государственная медицинская академияNeurotransmitters disturbances with the certain role of serotoninergic system are in the basis of pathogenesis of epilepsy. 46 patients (29 females, 17-males) with idiopatic generalized epilepsy (mean age 21,8 ± 1,82) were investigated. In 30,4% of patients depressive disorders were revealed. Significant decreasing of blood serotonin level in patients with during the interictal period which decreased more after the generalised convulsive and myoclonic seasures was found by the immune assay method.https://bulletin.ssmu.ru/jour/article/view/3446 |
| spellingShingle | N. B. Gubanova Yu. V. Karakulova Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy Бюллетень сибирской медицины |
| title | Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
| title_full | Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
| title_fullStr | Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
| title_full_unstemmed | Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
| title_short | Pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
| title_sort | pathogenical meaning of serotoninergic mechanisms in the development of idiopatic generalised forms of epilepsy |
| url | https://bulletin.ssmu.ru/jour/article/view/3446 |
| work_keys_str_mv | AT nbgubanova pathogenicalmeaningofserotoninergicmechanismsinthedevelopmentofidiopaticgeneralisedformsofepilepsy AT yuvkarakulova pathogenicalmeaningofserotoninergicmechanismsinthedevelopmentofidiopaticgeneralisedformsofepilepsy |