In vitro effects of ascorbic acid on viability and metabolism of patients’ osteosarcoma stem cells

In vitro effects of ascorbic acid on viability and metabolism of patients’ osteosarcoma stem cells

Stagnation in novelties of osteosarcoma (OS) treatment indicates the need for new therapeutic methods. OS cancer stem cells (OS-CSC) are taught to have the ability to self-renew and develop mechanisms of anticancer drug resistance, and this is why it is difficult to eradicate them. Their metabolism...

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Bibliographic Details
Main Authors: Jovičić Marijana Šimić, Pušić Maja, Antunović Maja, Ledinski Maja, Librenjak Lucija, Kolundžić Robert, Ribičić Tomislav, Trkulja Vladimir, Urlić Inga
Format: Article
Language:English
Published: Sciendo 2022-12-01
Series:Acta Pharmaceutica
Subjects:
osteosarcoma
cancer stem cells
tumor cell metabolism
ascorbic acid
Online Access:https://doi.org/10.2478/acph-2022-0040
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