Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up
Purpose of the Study. To compare the efficacy and safety of phacotrabeculectomy (P-Trab) and phacoemulsification with the ExPress (P-ExPress) mini glaucoma shunt implantation. Study Plan. Prospective randomized study. Material and Methods. 85 eyes with cataract and unregulated open angle glaucoma. T...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2015/720109 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832567255301357568 |
|---|---|
| author | Joanna Konopińska Marta Deniziak Emil Saeed Agnieszka Bartczak Renata Zalewska Zofia Mariak Marek Rękas |
| author_facet | Joanna Konopińska Marta Deniziak Emil Saeed Agnieszka Bartczak Renata Zalewska Zofia Mariak Marek Rękas |
| author_sort | Joanna Konopińska |
| collection | DOAJ |
| description | Purpose of the Study. To compare the efficacy and safety of phacotrabeculectomy (P-Trab) and phacoemulsification with the ExPress (P-ExPress) mini glaucoma shunt implantation. Study Plan. Prospective randomized study. Material and Methods. 85 eyes with cataract and unregulated open angle glaucoma. There were 46 eyes in the P-ExPress and 39 the P-Trab group. Intraocular pressure (IOP), the number of antiglaucoma medications, qualified and complete surgical success (defined as IOP ≤ 18.0 mmHg), visual acuity (CDVA), the number of endothelial cells, and postoperative complications and additional procedures were assessed. Results. After 12 months of observation, the average IOP in the P-Express group went from 26.4 ± 9.3 down to 17.1 ± 5 mmHg (P<0.05) and from 27.9 ± 12.9 down to 15.9 ± 2.7 mmHg in the P-Trab group (P<0.05). No significant differences in the amount of medications used after surgery and CDVA were discovered between the groups. In the P-ExPress group, greater loss of endothelial cells was noted (CDloss%), compared to the P-Trab group. Conclusions. Both P-ExPress and P-Trab have comparable efficacy and similar early postoperative complication profile. The presence of additional implant (as is the case of the ExPress mini glaucoma shunt implantation) may cause progressive loss of endothelial cells. |
| format | Article |
| id | doaj-art-b45f49ec9ca045d9b55b709f6c0345fa |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-b45f49ec9ca045d9b55b709f6c0345fa2025-02-03T01:01:58ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/720109720109Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-UpJoanna Konopińska0Marta Deniziak1Emil Saeed2Agnieszka Bartczak3Renata Zalewska4Zofia Mariak5Marek Rękas6Department of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24A Street, 15-276 Białystok, PolandDepartment of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24A Street, 15-276 Białystok, PolandDepartment of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24A Street, 15-276 Białystok, PolandDepartment of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24A Street, 15-276 Białystok, PolandDepartment of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24A Street, 15-276 Białystok, PolandDepartment of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24A Street, 15-276 Białystok, PolandDepartment of Ophthalmology, Military Institute of Medicine, Szaserów 128 Street, 04-141 Warsaw, PolandPurpose of the Study. To compare the efficacy and safety of phacotrabeculectomy (P-Trab) and phacoemulsification with the ExPress (P-ExPress) mini glaucoma shunt implantation. Study Plan. Prospective randomized study. Material and Methods. 85 eyes with cataract and unregulated open angle glaucoma. There were 46 eyes in the P-ExPress and 39 the P-Trab group. Intraocular pressure (IOP), the number of antiglaucoma medications, qualified and complete surgical success (defined as IOP ≤ 18.0 mmHg), visual acuity (CDVA), the number of endothelial cells, and postoperative complications and additional procedures were assessed. Results. After 12 months of observation, the average IOP in the P-Express group went from 26.4 ± 9.3 down to 17.1 ± 5 mmHg (P<0.05) and from 27.9 ± 12.9 down to 15.9 ± 2.7 mmHg in the P-Trab group (P<0.05). No significant differences in the amount of medications used after surgery and CDVA were discovered between the groups. In the P-ExPress group, greater loss of endothelial cells was noted (CDloss%), compared to the P-Trab group. Conclusions. Both P-ExPress and P-Trab have comparable efficacy and similar early postoperative complication profile. The presence of additional implant (as is the case of the ExPress mini glaucoma shunt implantation) may cause progressive loss of endothelial cells.http://dx.doi.org/10.1155/2015/720109 |
| spellingShingle | Joanna Konopińska Marta Deniziak Emil Saeed Agnieszka Bartczak Renata Zalewska Zofia Mariak Marek Rękas Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up Journal of Ophthalmology |
| title | Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up |
| title_full | Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up |
| title_fullStr | Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up |
| title_full_unstemmed | Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up |
| title_short | Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up |
| title_sort | prospective randomized study comparing combined phaco express and phacotrabeculectomy in open angle glaucoma treatment 12 month follow up |
| url | http://dx.doi.org/10.1155/2015/720109 |
| work_keys_str_mv | AT joannakonopinska prospectiverandomizedstudycomparingcombinedphacoexpressandphacotrabeculectomyinopenangleglaucomatreatment12monthfollowup AT martadeniziak prospectiverandomizedstudycomparingcombinedphacoexpressandphacotrabeculectomyinopenangleglaucomatreatment12monthfollowup AT emilsaeed prospectiverandomizedstudycomparingcombinedphacoexpressandphacotrabeculectomyinopenangleglaucomatreatment12monthfollowup AT agnieszkabartczak prospectiverandomizedstudycomparingcombinedphacoexpressandphacotrabeculectomyinopenangleglaucomatreatment12monthfollowup AT renatazalewska prospectiverandomizedstudycomparingcombinedphacoexpressandphacotrabeculectomyinopenangleglaucomatreatment12monthfollowup AT zofiamariak prospectiverandomizedstudycomparingcombinedphacoexpressandphacotrabeculectomyinopenangleglaucomatreatment12monthfollowup AT marekrekas prospectiverandomizedstudycomparingcombinedphacoexpressandphacotrabeculectomyinopenangleglaucomatreatment12monthfollowup |