Beyond Transactional Relationships in Community-Based Participatory Healthcare Research
Community-based public health and pharmaceutical clinical trial research often depend on transactional relationships, where researchers and participants exchange insights, data, and benefits. These exchanges shape trust, engagement, and ethical dynamics. However, while barriers to clinical trial par...
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Academic Research and Publishing UG (i. G.)
2025-07-01
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| Series: | Health Economics and Management Review |
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| Online Access: | https://armgpublishing.com/wp-content/uploads/2025/07/HEM_2_2025_2.pdf |
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| author | Darrell Norman Burrell C. Daniel Mullins Blessing Enobun |
| author_facet | Darrell Norman Burrell C. Daniel Mullins Blessing Enobun |
| author_sort | Darrell Norman Burrell |
| collection | DOAJ |
| description | Community-based public health and pharmaceutical clinical trial research often depend on transactional relationships, where researchers and participants exchange insights, data, and benefits. These exchanges shape trust, engagement, and ethical dynamics. However, while barriers to clinical trial participation and community engagement have been widely explored, the transactional essence of these interactions has limited academic discourse in existing literature. Effective management of transactional relationships is critical for advancing pharmaceutical research, particularly in drug absorption and metabolism, pharmacokinetics and dynamics, drug delivery systems, drug targeting, and nanotechnology. These fields rely on diverse participant inclusion to produce generalizable and representative data. For instance, equitable transactional dynamics enable researchers to gather essential insights into how genetic, environmental, and lifestyle factors affect drug metabolism, promoting advancements in personalized medicine. Building trust through transparent communication, which involves open and honest dialogue about the research process and its potential outcomes, encourages participant compliance, enhancing the reliability of data on drug behavior. Collaborative engagement also supports refining drug delivery systems and nanotechnology applications, ensuring that these innovations address real-world needs while mitigating risks and ethical concerns. This dynamic underscores the importance of cultural sensitivity in fostering trust and collaboration. By respecting and understanding diverse cultural backgrounds, researchers can build stronger relationships with participants, enhancing the quality and reliability of the data. By framing research interactions as transactional, this perspective expands public health research’s theoretical and practical understanding. This academic conversation fills a significant research void. It underscores the necessity of balancing power, fostering reciprocity, and respecting boundaries to enhance ethical and inclusive practices in clinical trials. This approach advances equitable, reflective practices prioritizing ethical transparency and collaborative engagement in community-based public health and pharmaceutical innovation. |
| format | Article |
| id | doaj-art-b45c61a503e2451dbb5749f4e76b014e |
| institution | DOAJ |
| issn | 2786-4626 2786-4634 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Academic Research and Publishing UG (i. G.) |
| record_format | Article |
| series | Health Economics and Management Review |
| spelling | doaj-art-b45c61a503e2451dbb5749f4e76b014e2025-08-20T03:12:50ZengAcademic Research and Publishing UG (i. G.)Health Economics and Management Review2786-46262786-46342025-07-0162173110.61093/hem.2025.2-02Beyond Transactional Relationships in Community-Based Participatory Healthcare ResearchDarrell Norman Burrell0https://orcid.org/0000-0002-4675-9544C. Daniel Mullins1https://orcid.org/0000-0003-4322-2490Blessing Enobun2https://orcid.org/0000-0003-1819-0562DHEd, PhD, DBA, Post Doctoral Fellow, The PATIENTS Program, School of Pharmacy, University of Maryland-Baltimore (USA) Visiting Researcher, Pellegrino Center for Clinical Bioethics, Georgetown University (USA) PhD, Executive Director, The PATIENTS Program, School of Pharmacy, University of Maryland-Baltimore (USA)Student, School of Pharmacy, University of Maryland-Baltimore (USA)Community-based public health and pharmaceutical clinical trial research often depend on transactional relationships, where researchers and participants exchange insights, data, and benefits. These exchanges shape trust, engagement, and ethical dynamics. However, while barriers to clinical trial participation and community engagement have been widely explored, the transactional essence of these interactions has limited academic discourse in existing literature. Effective management of transactional relationships is critical for advancing pharmaceutical research, particularly in drug absorption and metabolism, pharmacokinetics and dynamics, drug delivery systems, drug targeting, and nanotechnology. These fields rely on diverse participant inclusion to produce generalizable and representative data. For instance, equitable transactional dynamics enable researchers to gather essential insights into how genetic, environmental, and lifestyle factors affect drug metabolism, promoting advancements in personalized medicine. Building trust through transparent communication, which involves open and honest dialogue about the research process and its potential outcomes, encourages participant compliance, enhancing the reliability of data on drug behavior. Collaborative engagement also supports refining drug delivery systems and nanotechnology applications, ensuring that these innovations address real-world needs while mitigating risks and ethical concerns. This dynamic underscores the importance of cultural sensitivity in fostering trust and collaboration. By respecting and understanding diverse cultural backgrounds, researchers can build stronger relationships with participants, enhancing the quality and reliability of the data. By framing research interactions as transactional, this perspective expands public health research’s theoretical and practical understanding. This academic conversation fills a significant research void. It underscores the necessity of balancing power, fostering reciprocity, and respecting boundaries to enhance ethical and inclusive practices in clinical trials. This approach advances equitable, reflective practices prioritizing ethical transparency and collaborative engagement in community-based public health and pharmaceutical innovation.https://armgpublishing.com/wp-content/uploads/2025/07/HEM_2_2025_2.pdfparticipatory researchcommunity-based public health researchclinical trialstransactional relationships in researchethics in health researchresearch engagement sciencehelicopter research |
| spellingShingle | Darrell Norman Burrell C. Daniel Mullins Blessing Enobun Beyond Transactional Relationships in Community-Based Participatory Healthcare Research Health Economics and Management Review participatory research community-based public health research clinical trials transactional relationships in research ethics in health research research engagement science helicopter research |
| title | Beyond Transactional Relationships in Community-Based Participatory Healthcare Research |
| title_full | Beyond Transactional Relationships in Community-Based Participatory Healthcare Research |
| title_fullStr | Beyond Transactional Relationships in Community-Based Participatory Healthcare Research |
| title_full_unstemmed | Beyond Transactional Relationships in Community-Based Participatory Healthcare Research |
| title_short | Beyond Transactional Relationships in Community-Based Participatory Healthcare Research |
| title_sort | beyond transactional relationships in community based participatory healthcare research |
| topic | participatory research community-based public health research clinical trials transactional relationships in research ethics in health research research engagement science helicopter research |
| url | https://armgpublishing.com/wp-content/uploads/2025/07/HEM_2_2025_2.pdf |
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