Assessing in-vitro models for microglial development and fetal programming: a critical review

Assessing in-vitro models for microglial development and fetal programming: a critical review

This review evaluates in-vitro models for studying how maternal influences during pregnancy impact the development of offspring microglia, the immune cells of the central nervous system. The models examined include primary microglia cultures, microglia cell lines, iPSC-derived microglia, PBMC-induce...

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Bibliographic Details
Main Authors: Steven Schepanski, Gonza B. Ngoumou, Claudia Buss, Georg Seifert
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
microglia
brain development
in-vitro models
neuroimmunology and microglia
neurodevelopmental disorders
neuropsychiatry
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1538920/full
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