Integration of MRI radiomics and germline genetics to predict the IDH mutation status of gliomas

Integration of MRI radiomics and germline genetics to predict the IDH mutation status of gliomas

Abstract The molecular profiling of gliomas for isocitrate dehydrogenase (IDH) mutations currently relies on resected tumor samples, highlighting the need for non-invasive, preoperative biomarkers. We investigated the integration of glioma polygenic risk scores (PRS) and radiographic features for pr...

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Bibliographic Details
Main Authors: Taishi Nakase, George A. Henderson, Thomas Barba, Rohan Bareja, Geno Guerra, Qingyu Zhao, Stephen S. Francis, Olivier Gevaert, Linda Kachuri
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00980-z
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