Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications

Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications

Toll-like receptors (TLR), the key players of the innate immune system, contribute to the pathogenesis of atopic dermatitis (AD) through multiple pathways. TLRs play a crucial role in delaying barrier repair, promoting Th2-mediated dermatitis, shifting the response toward Th1 in the chronic phase, a...

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Bibliographic Details
Main Authors: Ahmad Vafaeian, Fateme Rajabi, Nima Rezaei
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Heliyon
Subjects:
Atopic dermatitis
Itch
Pathogenesis
Toll-like receptors
Innate immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025006061
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