Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Nonhormonal Contraception

Conclusion: This study highlights the potential of multilayered CAP/PCL electrospun fibers for intravaginal delivery of TFV and NFP, aimed at the pre-exposure prophylaxis of HIV-1 and prevention of unplanned pregnancy.

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Main Authors: Deborah A. Ogundemuren, Peace-Ofonabasi O. Bassey, Karamot O. Oyediran, Ohakwe G. Nmesoma, Dimitrios Tsamos, Alkiviadis Tsamis, Alexander E. Tsouknidas, Andrew N. Amenaghawon, Chukwuemeka P. Azubuike, Margaret O. Ilomuanya
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advances in Pharmacological and Pharmaceutical Sciences
Online Access:http://dx.doi.org/10.1155/adpp/4749211
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author Deborah A. Ogundemuren
Peace-Ofonabasi O. Bassey
Karamot O. Oyediran
Ohakwe G. Nmesoma
Dimitrios Tsamos
Alkiviadis Tsamis
Alexander E. Tsouknidas
Andrew N. Amenaghawon
Chukwuemeka P. Azubuike
Margaret O. Ilomuanya
author_facet Deborah A. Ogundemuren
Peace-Ofonabasi O. Bassey
Karamot O. Oyediran
Ohakwe G. Nmesoma
Dimitrios Tsamos
Alkiviadis Tsamis
Alexander E. Tsouknidas
Andrew N. Amenaghawon
Chukwuemeka P. Azubuike
Margaret O. Ilomuanya
author_sort Deborah A. Ogundemuren
collection DOAJ
description Conclusion: This study highlights the potential of multilayered CAP/PCL electrospun fibers for intravaginal delivery of TFV and NFP, aimed at the pre-exposure prophylaxis of HIV-1 and prevention of unplanned pregnancy.
format Article
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institution Kabale University
issn 2633-4690
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Advances in Pharmacological and Pharmaceutical Sciences
spelling doaj-art-b424d72331fa48b89ebc171bad8abaaf2025-08-20T03:29:47ZengWileyAdvances in Pharmacological and Pharmaceutical Sciences2633-46902025-01-01202510.1155/adpp/4749211Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Nonhormonal ContraceptionDeborah A. Ogundemuren0Peace-Ofonabasi O. Bassey1Karamot O. Oyediran2Ohakwe G. Nmesoma3Dimitrios Tsamos4Alkiviadis Tsamis5Alexander E. Tsouknidas6Andrew N. Amenaghawon7Chukwuemeka P. Azubuike8Margaret O. Ilomuanya9Department of Pharmaceutics and Pharmaceutical TechnologyDepartment of Pharmaceutics and Pharmaceutical TechnologyDepartment of Pharmaceutics and Pharmaceutical TechnologyDepartment of Pharmaceutics and Pharmaceutical TechnologyDepartment of Mechanical EngineeringDepartment of Mechanical EngineeringDepartment of Mechanical EngineeringDepartment of Chemical EngineeringDepartment of Pharmaceutics and Pharmaceutical TechnologyDepartment of Pharmaceutics and Pharmaceutical TechnologyConclusion: This study highlights the potential of multilayered CAP/PCL electrospun fibers for intravaginal delivery of TFV and NFP, aimed at the pre-exposure prophylaxis of HIV-1 and prevention of unplanned pregnancy.http://dx.doi.org/10.1155/adpp/4749211
spellingShingle Deborah A. Ogundemuren
Peace-Ofonabasi O. Bassey
Karamot O. Oyediran
Ohakwe G. Nmesoma
Dimitrios Tsamos
Alkiviadis Tsamis
Alexander E. Tsouknidas
Andrew N. Amenaghawon
Chukwuemeka P. Azubuike
Margaret O. Ilomuanya
Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Nonhormonal Contraception
Advances in Pharmacological and Pharmaceutical Sciences
title Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Nonhormonal Contraception
title_full Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Nonhormonal Contraception
title_fullStr Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Nonhormonal Contraception
title_full_unstemmed Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Nonhormonal Contraception
title_short Innovative Multilayered Electrospun Fiber Systems for Dual-Action HIV Prophylaxis and Nonhormonal Contraception
title_sort innovative multilayered electrospun fiber systems for dual action hiv prophylaxis and nonhormonal contraception
url http://dx.doi.org/10.1155/adpp/4749211
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