A cross-sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine department
Introduction: The detection of schistosome eggs in stool or urine specimens is the most used technique in population-based studies, while the rectal mucosal biopsy is the commonly used technique in hospital setting. The aim of this hospital-based study was to describe the epidemiological aspects of...
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African Field Epidemiology Network
2025-05-01
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| Series: | Journal of Interventional Epidemiology and Public Health |
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| Online Access: | https://afenet-journal.org/a-cross-sectional-analysis-of-schistosomiasis-case-detection-by-rectal-mucosal-biopsy-among-patients-attending-the-digestive-endoscopy-unit-of-the-internal-medicine-department/ |
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| author | Kaly Keïta Stéphane Loique Djeugoué Boua Daoud Camara Alassane Alfousséni Doumbia Cheick Oumar Kamissoko Oumar Sandji Adama Sinayoko Abdoulaye Keïta Maïmouna Togo Charles Dara Garan Dabo Abdoulaye Mamadou Traoré Ibrahima Amadou Dembélé Djibril Sy Djénèbou Traoré Assétou Soukho Kaya Mamadou Dembélé Abdoulaye Kassoum Koné Daouda Kassoum Minta Hamar Alassane Traoré |
| author_facet | Kaly Keïta Stéphane Loique Djeugoué Boua Daoud Camara Alassane Alfousséni Doumbia Cheick Oumar Kamissoko Oumar Sandji Adama Sinayoko Abdoulaye Keïta Maïmouna Togo Charles Dara Garan Dabo Abdoulaye Mamadou Traoré Ibrahima Amadou Dembélé Djibril Sy Djénèbou Traoré Assétou Soukho Kaya Mamadou Dembélé Abdoulaye Kassoum Koné Daouda Kassoum Minta Hamar Alassane Traoré |
| author_sort | Kaly Keïta |
| collection | DOAJ |
| description | Introduction: The detection of schistosome eggs in stool or urine specimens is the most used technique in population-based studies, while the rectal mucosal biopsy is the commonly used technique in hospital setting. The aim of this hospital-based study was to describe the epidemiological aspects of schistosomiasis.
Methods: A cross-sectional study with retrospective data collection was conducted between January 01, 2011 to December 31, 2017 among patients who have undergone endoscopy and rectal mucosal biopsy at the digestive endoscopy Unit of internal medicine Department at the University Hospital Center Point G. We conducted univariate analysis to obtain mean and standard deviation for quantitative data and numbers and percentages for qualitative data. In the bivariate analysis, the Chi-square and Fisher´s exact tests were used to assess the statistical significance and strength of the associations between the categorical independent variables and the outcome variables. Variables with a Chi-square test with p < 0.2 at bivariate analysis were included in a multivariate logistic regression.
Results: 840 rectal mucosal biopsies reports (sex-ratio= 2.4, mean age= 30,99 ± 16, 66 years) were considered for analysis. Clinical indications were dominated by schistosomiasis related symptoms (46.0%), edematous syndrome (10.4%). 306 (36,4%) rectal mucosal biopsies were positive for Schistosoma haematobium (36.4%) and 8 (0.95%) for schistosoma mansoni. The highest positivity rates of Schistosoma haematobium and Schistosoma mansoni were observed in 2015 with 42.67% and in 2016 with 3.77%. The positivity rate of Schistosoma haematobium was 1.44 times more common in males than in females (p=0.030). The highest positivity rate of Schistosoma haematobium (90.24%) and Schistosoma mansoni (71.43%) were observed in patients under 50 years and 24 years, respectively. Factors independently associated with Schistosoma heamatobium infection positivity were: age group of 50 – 74 years (p=0.035), Malinké ethnic group (p=0.031), Soninké ethnic group (p=0.023), Segou residents (p=0.000), Mopti residents (p=0.039), pupil/student (p=0.003), trader (p=0.001) and hematuria (p=0.029).
Conclusion: The analysis of rectal mucosal biopsy showed a higher positivity rate of Schistosoma haematobium than of Schistosoma mansoni. The annual realization rate of rectal mucosal biopsy decreased from 2011 to 2017. The annual positivity rate of schistosomiasis is very disparate. |
| format | Article |
| id | doaj-art-b41954b7f48b49dfad2913a6140ef576 |
| institution | Kabale University |
| issn | 2664-2824 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | African Field Epidemiology Network |
| record_format | Article |
| series | Journal of Interventional Epidemiology and Public Health |
| spelling | doaj-art-b41954b7f48b49dfad2913a6140ef5762025-08-20T03:49:18ZengAfrican Field Epidemiology NetworkJournal of Interventional Epidemiology and Public Health2664-28242025-05-01821https://doi.org/10.37432/jieph-d-24-02023A cross-sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine departmentKaly Keïta0Stéphane Loique Djeugoué1Boua Daoud Camara2Alassane Alfousséni Doumbia3Cheick Oumar Kamissoko4Oumar Sandji5Adama Sinayoko6Abdoulaye Keïta7Maïmouna Togo8Charles Dara9Garan Dabo10Abdoulaye Mamadou Traoré11Ibrahima Amadou Dembélé12Djibril Sy13Djénèbou Traoré14 Assétou Soukho Kaya15Mamadou Dembélé16Abdoulaye Kassoum Koné17Daouda Kassoum Minta18Hamar Alassane Traoré19Department of Internal Medicine, University Hospital Center of the Point G, Bamako, MaliDepartment of Internal Medicine, University Hospital Center of the Point G, Bamako, MaliDepartment of Internal Medicine, Nianankoro Fomba Hospital, Ségou, MaliDepartment of Medicine, University Hospital Center “Hôpital du Mali”, Bamako, MaliSélingué Reference Health Center, MaliDepartment of Medicine, Referral Health Center of Commune 1, Bamako, Mali,Department of Internal Medicine, University Hospital Center of the Point G, Bamako, MaliDrug and Laboratory Unit, Regional Health Department of Koulikoro, MaliDepartment of Neurology, University Hospital Center of Gabriel Touré, Bamako, MaliDepartment of Medicine, University Hospital Center “Hôpital du Mali”, Bamako, MaliDepartment of Medicine, University Hospital Center “Hôpital du Mali”, Bamako, MaliDepartment of Infectious Diseases, University Hospital Center of the Point G, Bamako, Mali,Department of Internal Medicine, University Hospital Center of the Point G, Bamako, MaliFaculty of Medicine and Odontostomatology (FMOS), University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.Faculty of Medicine and Odontostomatology (FMOS), University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.Faculty of Medicine and Odontostomatology (FMOS), University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.Faculty of Medicine and Odontostomatology (FMOS), University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.Faculty of Medicine and Odontostomatology (FMOS), University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.Faculty of Medicine and Odontostomatology (FMOS), University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.Faculty of Medicine and Odontostomatology (FMOS), University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.Introduction: The detection of schistosome eggs in stool or urine specimens is the most used technique in population-based studies, while the rectal mucosal biopsy is the commonly used technique in hospital setting. The aim of this hospital-based study was to describe the epidemiological aspects of schistosomiasis. Methods: A cross-sectional study with retrospective data collection was conducted between January 01, 2011 to December 31, 2017 among patients who have undergone endoscopy and rectal mucosal biopsy at the digestive endoscopy Unit of internal medicine Department at the University Hospital Center Point G. We conducted univariate analysis to obtain mean and standard deviation for quantitative data and numbers and percentages for qualitative data. In the bivariate analysis, the Chi-square and Fisher´s exact tests were used to assess the statistical significance and strength of the associations between the categorical independent variables and the outcome variables. Variables with a Chi-square test with p < 0.2 at bivariate analysis were included in a multivariate logistic regression. Results: 840 rectal mucosal biopsies reports (sex-ratio= 2.4, mean age= 30,99 ± 16, 66 years) were considered for analysis. Clinical indications were dominated by schistosomiasis related symptoms (46.0%), edematous syndrome (10.4%). 306 (36,4%) rectal mucosal biopsies were positive for Schistosoma haematobium (36.4%) and 8 (0.95%) for schistosoma mansoni. The highest positivity rates of Schistosoma haematobium and Schistosoma mansoni were observed in 2015 with 42.67% and in 2016 with 3.77%. The positivity rate of Schistosoma haematobium was 1.44 times more common in males than in females (p=0.030). The highest positivity rate of Schistosoma haematobium (90.24%) and Schistosoma mansoni (71.43%) were observed in patients under 50 years and 24 years, respectively. Factors independently associated with Schistosoma heamatobium infection positivity were: age group of 50 – 74 years (p=0.035), Malinké ethnic group (p=0.031), Soninké ethnic group (p=0.023), Segou residents (p=0.000), Mopti residents (p=0.039), pupil/student (p=0.003), trader (p=0.001) and hematuria (p=0.029). Conclusion: The analysis of rectal mucosal biopsy showed a higher positivity rate of Schistosoma haematobium than of Schistosoma mansoni. The annual realization rate of rectal mucosal biopsy decreased from 2011 to 2017. The annual positivity rate of schistosomiasis is very disparate.https://afenet-journal.org/a-cross-sectional-analysis-of-schistosomiasis-case-detection-by-rectal-mucosal-biopsy-among-patients-attending-the-digestive-endoscopy-unit-of-the-internal-medicine-department/neglected tropical diseasesschistosomiasisparasitic diseasesepidemiologyinternal medicine |
| spellingShingle | Kaly Keïta Stéphane Loique Djeugoué Boua Daoud Camara Alassane Alfousséni Doumbia Cheick Oumar Kamissoko Oumar Sandji Adama Sinayoko Abdoulaye Keïta Maïmouna Togo Charles Dara Garan Dabo Abdoulaye Mamadou Traoré Ibrahima Amadou Dembélé Djibril Sy Djénèbou Traoré Assétou Soukho Kaya Mamadou Dembélé Abdoulaye Kassoum Koné Daouda Kassoum Minta Hamar Alassane Traoré A cross-sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine department Journal of Interventional Epidemiology and Public Health neglected tropical diseases schistosomiasis parasitic diseases epidemiology internal medicine |
| title | A cross-sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine department |
| title_full | A cross-sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine department |
| title_fullStr | A cross-sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine department |
| title_full_unstemmed | A cross-sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine department |
| title_short | A cross-sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine department |
| title_sort | cross sectional analysis of schistosomiasis case detection by rectal mucosal biopsy among patients attending the digestive endoscopy unit of the internal medicine department |
| topic | neglected tropical diseases schistosomiasis parasitic diseases epidemiology internal medicine |
| url | https://afenet-journal.org/a-cross-sectional-analysis-of-schistosomiasis-case-detection-by-rectal-mucosal-biopsy-among-patients-attending-the-digestive-endoscopy-unit-of-the-internal-medicine-department/ |
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