Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis.

Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis.

FrpB is an outer membrane transporter from Neisseria meningitidis, the causative agent of meningococcal meningitis. It is a member of the TonB-dependent transporter (TBDT) family and is responsible for iron uptake into the periplasm. FrpB is subject to a high degree of antigenic variation, principal...

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Bibliographic Details
Main Authors: Muhammad Saleem, Stephen M Prince, Stephen E J Rigby, Muhammad Imran, Hema Patel, Hannah Chan, Holly Sanders, Martin C J Maiden, Ian M Feavers, Jeremy P Derrick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0056746&type=printable
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