Ultra-Sensitive Detection of Chloramphenicol by CdS@NiMoS Nanorods-Based Photoelectrochemical Aptasensor
A novel nanomaterial photoelectrochemical aptamer sensor based on CdS@NiMoS heterojunction nanocomposites was constructed for highly sensitive detection of chloramphenicol (CAP) in antibiotic residues. Through optimization of the material synthesis process, the optimal doping ratio of MoS<sub>...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-07-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/15/7/454 |
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| author | Hebin Sun Yimeng Sun Tong Qi Zhenyu Wang Jianlong Zhao Lijuan Liang |
| author_facet | Hebin Sun Yimeng Sun Tong Qi Zhenyu Wang Jianlong Zhao Lijuan Liang |
| author_sort | Hebin Sun |
| collection | DOAJ |
| description | A novel nanomaterial photoelectrochemical aptamer sensor based on CdS@NiMoS heterojunction nanocomposites was constructed for highly sensitive detection of chloramphenicol (CAP) in antibiotic residues. Through optimization of the material synthesis process, the optimal doping ratio of MoS<sub>2</sub> to Ni<sup>3+</sup> (70% MoS<sub>2</sub> and 10% Ni<sup>3+</sup>) was identified, which significantly enhanced the photogenerated carrier separation efficiency. In thin-film preparation, comparative analysis of four film-forming methods led to the determination of an optimal process with stability. To achieve highly specific CAP detection, the nanocomposite chip was integrated with nucleic acid aptamer biorecognition elements within a standard three-electrode detection system. Experimental results demonstrated a linear response (R<sup>2</sup> = 0.998) in the 0.1–2 μM concentration range, with a detection limit of 3.69 nM (3σ/S). |
| format | Article |
| id | doaj-art-b3f89bf711dc4cf9a21782bd450f893b |
| institution | DOAJ |
| issn | 2079-6374 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj-art-b3f89bf711dc4cf9a21782bd450f893b2025-08-20T02:45:34ZengMDPI AGBiosensors2079-63742025-07-0115745410.3390/bios15070454Ultra-Sensitive Detection of Chloramphenicol by CdS@NiMoS Nanorods-Based Photoelectrochemical AptasensorHebin Sun0Yimeng Sun1Tong Qi2Zhenyu Wang3Jianlong Zhao4Lijuan Liang5State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, ChinaState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, ChinaState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, ChinaSchool of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, ChinaState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, ChinaState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, ChinaA novel nanomaterial photoelectrochemical aptamer sensor based on CdS@NiMoS heterojunction nanocomposites was constructed for highly sensitive detection of chloramphenicol (CAP) in antibiotic residues. Through optimization of the material synthesis process, the optimal doping ratio of MoS<sub>2</sub> to Ni<sup>3+</sup> (70% MoS<sub>2</sub> and 10% Ni<sup>3+</sup>) was identified, which significantly enhanced the photogenerated carrier separation efficiency. In thin-film preparation, comparative analysis of four film-forming methods led to the determination of an optimal process with stability. To achieve highly specific CAP detection, the nanocomposite chip was integrated with nucleic acid aptamer biorecognition elements within a standard three-electrode detection system. Experimental results demonstrated a linear response (R<sup>2</sup> = 0.998) in the 0.1–2 μM concentration range, with a detection limit of 3.69 nM (3σ/S).https://www.mdpi.com/2079-6374/15/7/454CdS@NiMoSchloramphenicolaptsensorPEC |
| spellingShingle | Hebin Sun Yimeng Sun Tong Qi Zhenyu Wang Jianlong Zhao Lijuan Liang Ultra-Sensitive Detection of Chloramphenicol by CdS@NiMoS Nanorods-Based Photoelectrochemical Aptasensor Biosensors CdS@NiMoS chloramphenicol aptsensor PEC |
| title | Ultra-Sensitive Detection of Chloramphenicol by CdS@NiMoS Nanorods-Based Photoelectrochemical Aptasensor |
| title_full | Ultra-Sensitive Detection of Chloramphenicol by CdS@NiMoS Nanorods-Based Photoelectrochemical Aptasensor |
| title_fullStr | Ultra-Sensitive Detection of Chloramphenicol by CdS@NiMoS Nanorods-Based Photoelectrochemical Aptasensor |
| title_full_unstemmed | Ultra-Sensitive Detection of Chloramphenicol by CdS@NiMoS Nanorods-Based Photoelectrochemical Aptasensor |
| title_short | Ultra-Sensitive Detection of Chloramphenicol by CdS@NiMoS Nanorods-Based Photoelectrochemical Aptasensor |
| title_sort | ultra sensitive detection of chloramphenicol by cds nimos nanorods based photoelectrochemical aptasensor |
| topic | CdS@NiMoS chloramphenicol aptsensor PEC |
| url | https://www.mdpi.com/2079-6374/15/7/454 |
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