Phacoviscocanalostomy versus phacoemulsification alone for glaucoma associated with cataract: a meta-analysis

Phacoviscocanalostomy versus phacoemulsification alone for glaucoma associated with cataract: a meta-analysis

ABSTRACT Objective: This systematic review and meta-analysis compare the safety and efficacy of phacoemulsification alone versus combined phacoviscocanalostomy in glaucoma and cataract patients. Methods: We followed PRISMA guidelines. PubMed®, Web of Science, Cochrane, and Embase were searched for...

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Main Authors: Dillan Cunha Amaral, Milton Ruiz Alves, Karina de Oliveira Caneca, Ana Luiza Machado Ribeiro Pimentel, Bruna Gabriel Miranda, Adroaldo de Alencar Costa Filho, Mário Luiz Ribeiro Monteiro, Jaime Guedes, Ricardo Noguera Louzada
Format: Article
Language:English
Published: Sociedade Brasileira de Oftalmologia 2025-06-01
Series:Revista Brasileira de Oftalmologia
Subjects:
Glaucoma
open angle
Cataract
Phacoemulsification
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802025000100301&lng=en&tlng=en
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Summary:ABSTRACT Objective: This systematic review and meta-analysis compare the safety and efficacy of phacoemulsification alone versus combined phacoviscocanalostomy in glaucoma and cataract patients. Methods: We followed PRISMA guidelines. PubMed®, Web of Science, Cochrane, and Embase were searched for randomized clinical trial and non-randomized clinical trial studies comparing phaco versus phacoviscocanalostomy in patients with any glaucoma and cataract type. Statistical analysis was conducted using RevMan software. Results: The study included 889 patients from one randomized clinical trial and three non-randomized clinical trials studies, of whom 499 (56.1%) received phacoviscocanalostomy. Patients treated with phacoviscocanalostomy had significantly lower intraocular pressure at 1 (mean difference: 3.90; p < 0.00001), 3 (mean difference: 2.52; p = 0.03), 6 (mean difference: 1.90; p = 0.04), 18 (mean difference: 3.23; p < 0.00001) and 24 months (mean difference: 2.55; p < 0.00001), except for 12 months (mean difference: 2.26; p = 0.08). A lower medication at six months (mean difference: 0.68; p < 0.00001), no difference in the visual acuity (mean difference: −0.02; p = 0.77), and a higher rate of adverse events (odds ratios: 236.96; p = 0.004) were found. Conclusions: The combined phacoviscocalanostomy approach showed positive outcomes, without increasing the severe complication rates. Registry PROSPERO - CRD42024501313
ISSN:1982-8551

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