Time to invest in cholera

Summary: The recent surge in cholera cases globally calls for urgent evaluation of current approaches to prevention and control of the disease. Malawi was one of the worst affected countries in 2022–2023 with the highest number of deaths due to cholera in the world. In this personal view, we look at...

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Main Authors: Rebecca C. Stout, Nicholas Feasey, Marion Péchayre, Nicholas Thomson, Benson Z. Chilima
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:EClinicalMedicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589537024006230
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author Rebecca C. Stout
Nicholas Feasey
Marion Péchayre
Nicholas Thomson
Benson Z. Chilima
author_facet Rebecca C. Stout
Nicholas Feasey
Marion Péchayre
Nicholas Thomson
Benson Z. Chilima
author_sort Rebecca C. Stout
collection DOAJ
description Summary: The recent surge in cholera cases globally calls for urgent evaluation of current approaches to prevention and control of the disease. Malawi was one of the worst affected countries in 2022–2023 with the highest number of deaths due to cholera in the world. In this personal view, we look at Malawi as a case example to illustrate how current approaches lack sufficient investment. We review the history of cholera in Malawi and compare previous outbreaks to the 2022/23 outbreak. We discuss contributing factors to the outbreak including a lack of investment in water, sanitation and hygiene (both historically and currently), human resource constraints, and the market structures which make accessing oral cholera vaccine challenging both in the midst of an ongoing outbreak and as a preventative approach. We call for international action to address the economic and structural challenges underlying cholera persistence and propose solutions to prevent future epidemics and to eliminate cholera as a public health threat.
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institution Kabale University
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spelling doaj-art-b3f39ecee19c438591371fd8fb511a142025-01-19T06:26:30ZengElsevierEClinicalMedicine2589-53702025-02-0180103044Time to invest in choleraRebecca C. Stout0Nicholas Feasey1Marion Péchayre2Nicholas Thomson3Benson Z. Chilima4Imperial College London, Department of Infectious Diseases, Faculty of Medicine, Exhibition Road, South Kensington, London SW7 2BX, UK; Corresponding author.Malawi Liverpool Wellcome Programme, Kamuzu University Health Sciences, Queen Elizabeth Central Hospital Campus, Chipatala Avenue, P.O. Box 30096 Chichiri, Blantyre, Malawi; School of Medicine, University of St Andrews, Medical and Biological Sciences Building, North Haugh, St Andrews, Fife KY16 9TF, UKDirector of Studies, CRASH, Médecins Sans Frontières, SwitzerlandHead of Parasites and Microbes Programme and Group Leader, Parasites and Microbes Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK; London School of Hygiene and Tropical Medicine, Keppel Street, London WC13 7HT, UKFormer Director of Public Health Institute of Malawi, Ministry of Health, Public Health Institute of Malawi, P.O. Box 30377, Lilongwe, MalawiSummary: The recent surge in cholera cases globally calls for urgent evaluation of current approaches to prevention and control of the disease. Malawi was one of the worst affected countries in 2022–2023 with the highest number of deaths due to cholera in the world. In this personal view, we look at Malawi as a case example to illustrate how current approaches lack sufficient investment. We review the history of cholera in Malawi and compare previous outbreaks to the 2022/23 outbreak. We discuss contributing factors to the outbreak including a lack of investment in water, sanitation and hygiene (both historically and currently), human resource constraints, and the market structures which make accessing oral cholera vaccine challenging both in the midst of an ongoing outbreak and as a preventative approach. We call for international action to address the economic and structural challenges underlying cholera persistence and propose solutions to prevent future epidemics and to eliminate cholera as a public health threat.http://www.sciencedirect.com/science/article/pii/S2589537024006230Vibrio choleraeCholeraOutbreaksPublic Health
spellingShingle Rebecca C. Stout
Nicholas Feasey
Marion Péchayre
Nicholas Thomson
Benson Z. Chilima
Time to invest in cholera
EClinicalMedicine
Vibrio cholerae
Cholera
Outbreaks
Public Health
title Time to invest in cholera
title_full Time to invest in cholera
title_fullStr Time to invest in cholera
title_full_unstemmed Time to invest in cholera
title_short Time to invest in cholera
title_sort time to invest in cholera
topic Vibrio cholerae
Cholera
Outbreaks
Public Health
url http://www.sciencedirect.com/science/article/pii/S2589537024006230
work_keys_str_mv AT rebeccacstout timetoinvestincholera
AT nicholasfeasey timetoinvestincholera
AT marionpechayre timetoinvestincholera
AT nicholasthomson timetoinvestincholera
AT bensonzchilima timetoinvestincholera