New opportunities for the synthesis of quinoxaline derivatives
Convenient methods for the synthesis of quinoxaline derivatives with the use of nucleophilic aromatic substitution of hydrogen in heteroaromatic part of molecule in conditions of the acid catalysis were elaborated. The reactions of substitution of fluorine with amines in aromatic ring of 6,7-difluor...
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| Format: | Article |
| Language: | English |
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Ural Federal University
2019-02-01
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| Series: | Chimica Techno Acta |
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| Online Access: | https://chimicatechnoacta.ru/article/view/3690 |
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| author | Olga S. Koptyaeva Yuriy A. Azev Yuriy M. Shafran Tatyana A. Pospelova Oleg N. Chupakhin |
| author_facet | Olga S. Koptyaeva Yuriy A. Azev Yuriy M. Shafran Tatyana A. Pospelova Oleg N. Chupakhin |
| author_sort | Olga S. Koptyaeva |
| collection | DOAJ |
| description | Convenient methods for the synthesis of quinoxaline derivatives with the use of nucleophilic aromatic substitution of hydrogen in heteroaromatic part of molecule in conditions of the acid catalysis were elaborated. The reactions of substitution of fluorine with amines in aromatic ring of 6,7-difluoroquinoxaline with the formation of monofluoro derivatives were studied. |
| format | Article |
| id | doaj-art-b3ec228fddcc4241a0ddcd4e32640d60 |
| institution | OA Journals |
| issn | 2411-1414 |
| language | English |
| publishDate | 2019-02-01 |
| publisher | Ural Federal University |
| record_format | Article |
| series | Chimica Techno Acta |
| spelling | doaj-art-b3ec228fddcc4241a0ddcd4e32640d602025-08-20T02:23:14ZengUral Federal UniversityChimica Techno Acta2411-14142019-02-0161122310.15826/chimtech.2019.6.1.022997New opportunities for the synthesis of quinoxaline derivativesOlga S. Koptyaeva0Yuriy A. Azev1Yuriy M. Shafran2Tatyana A. Pospelova3Oleg N. Chupakhin4Ural Federal University, EkaterinburgUral Federal University, EkaterinburgUral Federal University, EkaterinburgUral Federal University, EkaterinburgUral Federal University, Ekaterinburg; Postovsky Institute of Organic Synthesis, EkaterinburgConvenient methods for the synthesis of quinoxaline derivatives with the use of nucleophilic aromatic substitution of hydrogen in heteroaromatic part of molecule in conditions of the acid catalysis were elaborated. The reactions of substitution of fluorine with amines in aromatic ring of 6,7-difluoroquinoxaline with the formation of monofluoro derivatives were studied.https://chimicatechnoacta.ru/article/view/3690quinoxalines6,7-difluoroquinoxalinesquinoxalin-2-ones6,7-dufluoroquinoxalin-2-onesnucleophiles |
| spellingShingle | Olga S. Koptyaeva Yuriy A. Azev Yuriy M. Shafran Tatyana A. Pospelova Oleg N. Chupakhin New opportunities for the synthesis of quinoxaline derivatives Chimica Techno Acta quinoxalines 6,7-difluoroquinoxalines quinoxalin-2-ones 6,7-dufluoroquinoxalin-2-ones nucleophiles |
| title | New opportunities for the synthesis of quinoxaline derivatives |
| title_full | New opportunities for the synthesis of quinoxaline derivatives |
| title_fullStr | New opportunities for the synthesis of quinoxaline derivatives |
| title_full_unstemmed | New opportunities for the synthesis of quinoxaline derivatives |
| title_short | New opportunities for the synthesis of quinoxaline derivatives |
| title_sort | new opportunities for the synthesis of quinoxaline derivatives |
| topic | quinoxalines 6,7-difluoroquinoxalines quinoxalin-2-ones 6,7-dufluoroquinoxalin-2-ones nucleophiles |
| url | https://chimicatechnoacta.ru/article/view/3690 |
| work_keys_str_mv | AT olgaskoptyaeva newopportunitiesforthesynthesisofquinoxalinederivatives AT yuriyaazev newopportunitiesforthesynthesisofquinoxalinederivatives AT yuriymshafran newopportunitiesforthesynthesisofquinoxalinederivatives AT tatyanaapospelova newopportunitiesforthesynthesisofquinoxalinederivatives AT olegnchupakhin newopportunitiesforthesynthesisofquinoxalinederivatives |