The frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in Slemani city /Iraq
Background and objective: Thyroid disorders caused by blood transfusion in thalassemia patients could affect human health and growth, this study was conducted to determine the frequency of clinical and subclinical hypothyroidism in blood transfusion-dependent thalassemia patients in the city of Sle...
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Kurdistan Higher Council Of Medical Specialties
2024-06-01
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| Series: | Advanced Medical Journal |
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| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/425 |
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| author | Dezheen Jamal Mohammed Rashid Kawa Muhamad Ameen Nawsherwan Sadiq Mohammed |
| author_facet | Dezheen Jamal Mohammed Rashid Kawa Muhamad Ameen Nawsherwan Sadiq Mohammed |
| author_sort | Dezheen Jamal Mohammed Rashid |
| collection | DOAJ |
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Background and objective: Thyroid disorders caused by blood transfusion in thalassemia patients could affect human health and growth, this study was conducted to determine the frequency of clinical and subclinical hypothyroidism in blood transfusion-dependent thalassemia patients in the city of Slemani, Kurdistan Region, Iraq.
Methods: The current study is a retrospective cross-sectional study (comparative analysis) conducted in Slemani center for thalassemia patients and congenital blood, between December 2021 and July 2022. Participants included l07 thalassemia patients with medical records the sampling method was a convenience method. The data was collected through the review of patients' files and blood tests, including( thyroid hormones, hemoglobin level, serum ferritin level), with a questionnaire that was completed through an interview with the patients.
Results: The results of thyroid function tests have shown that 21/107 pateints (19.6%) have hypothyroidism, 6 patients have overt hypothyroidism, and 15 patients have subclinical showed that 23/107 patients and 4/107 patients had hight and low levels,respectively, and there was statistically a significant difference in the average Thyroid stimulating hormone and serum thyroxin levels in two groups of hypothyroid and euthyroid patients and mean ferritine serum level between these two groups was 2166.7±2174.8 and 2068.37±1919.97 respictively ,which was not a statistically significant difference .
Conclusion: Considering the high prevalence of hypothyroidism in thalassemia patients, measuring Thyroid stimulating hormone and thyroxin can be very important and vital in the initial screenings,effective treatment and follow-up of patients.
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| format | Article |
| id | doaj-art-b3e9bf26430a45c3a68ba7aab0e1f5e8 |
| institution | OA Journals |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-b3e9bf26430a45c3a68ba7aab0e1f5e82025-08-20T02:12:59ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802024-06-019210.56056/amj.2024.265426The frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in Slemani city /IraqDezheen Jamal Mohammed Rashid0Kawa Muhamad Ameen1Nawsherwan Sadiq Mohammed2MBChB, KHCMS Candidate/ Clinical Hematology. Hiwa Cancer hospital, Slemani, Kurdistan Region,IraqMBChB, FRCP, PhD Assistant professor of clinical hematology , Department of Medicine, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region, Iraq.MBChB, FIBMS-path, Consultant hematopathologist Department of Pathology, Nanakali hospital, Erbil, Kurdistan Region, Iraq Background and objective: Thyroid disorders caused by blood transfusion in thalassemia patients could affect human health and growth, this study was conducted to determine the frequency of clinical and subclinical hypothyroidism in blood transfusion-dependent thalassemia patients in the city of Slemani, Kurdistan Region, Iraq. Methods: The current study is a retrospective cross-sectional study (comparative analysis) conducted in Slemani center for thalassemia patients and congenital blood, between December 2021 and July 2022. Participants included l07 thalassemia patients with medical records the sampling method was a convenience method. The data was collected through the review of patients' files and blood tests, including( thyroid hormones, hemoglobin level, serum ferritin level), with a questionnaire that was completed through an interview with the patients. Results: The results of thyroid function tests have shown that 21/107 pateints (19.6%) have hypothyroidism, 6 patients have overt hypothyroidism, and 15 patients have subclinical showed that 23/107 patients and 4/107 patients had hight and low levels,respectively, and there was statistically a significant difference in the average Thyroid stimulating hormone and serum thyroxin levels in two groups of hypothyroid and euthyroid patients and mean ferritine serum level between these two groups was 2166.7±2174.8 and 2068.37±1919.97 respictively ,which was not a statistically significant difference . Conclusion: Considering the high prevalence of hypothyroidism in thalassemia patients, measuring Thyroid stimulating hormone and thyroxin can be very important and vital in the initial screenings,effective treatment and follow-up of patients. https://amj.khcms.edu.krd/index.php/main/article/view/425HypothyroidismThyroid Stimulating Hormone (TSH)Transfusion Dependent Thalassemia (TDT)Serum Free Thyroxin (FT4) |
| spellingShingle | Dezheen Jamal Mohammed Rashid Kawa Muhamad Ameen Nawsherwan Sadiq Mohammed The frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in Slemani city /Iraq Advanced Medical Journal Hypothyroidism Thyroid Stimulating Hormone (TSH) Transfusion Dependent Thalassemia (TDT) Serum Free Thyroxin (FT4) |
| title | The frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in Slemani city /Iraq |
| title_full | The frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in Slemani city /Iraq |
| title_fullStr | The frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in Slemani city /Iraq |
| title_full_unstemmed | The frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in Slemani city /Iraq |
| title_short | The frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in Slemani city /Iraq |
| title_sort | frequency of clinical and subclinical hypothyroidism in transfusion dependent thalassemia patients in slemani city iraq |
| topic | Hypothyroidism Thyroid Stimulating Hormone (TSH) Transfusion Dependent Thalassemia (TDT) Serum Free Thyroxin (FT4) |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/425 |
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