Transcriptomic profiling of blood from autoimmune hepatitis patients reveals potential mechanisms with implications for management.

Transcriptomic profiling of blood from autoimmune hepatitis patients reveals potential mechanisms with implications for management.

Autoimmune hepatitis (AIH) is a poorly understood, chronic disease, for which corticosteroids are still the mainstay of therapy and most patients undergo liver biopsy to obtain a diagnosis. We aimed to determine if there was a transcriptomic signature of AIH in the peripheral blood and investigate u...

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Bibliographic Details
Main Authors: Michele May-Sien Tana, Arielle Klepper, Amy Lyden, Angela Oliveira Pisco, Maira Phelps, Breann McGee, Kelsey Green, Sandy Feng, Joseph DeRisi, Emily Dawn Crawford, Craig S Lammert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0264307&type=printable
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