Treatment outcomes for adult patients with localized osteosarcoma treated with chemotherapy without methotrexate at a public hospital in Brazil

Treatment outcomes for adult patients with localized osteosarcoma treated with chemotherapy without methotrexate at a public hospital in Brazil

Introduction: Standard treatment for pediatric patients with localized osteosarcoma includes high-dose methotrexate (HDMTX), and cure rates greater than 60% are observed. However, in adult patients, the toxicity profile limits the use of HDMTX and the drug is usually excluded from chemotherapy proto...

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Main Authors: Marilia Polo Minguete-e-Silva, Renata Rodrigues da Cunha Colombo Bonadio, Gustavo Matos, Diego de Araújo Toloi, Rodrigo Ramella Munhoz, Mirella Nardo, Daniel Rebolledo, Luiz Filipe Marques Correa, Andre Mathias Baptista, Caroline Chaul de Lima Barbosa Zampieri, Olavo Feher, Veridiana Pires de Camargo
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2021-10-01
Series:Brazilian Journal of Oncology
Subjects:
osteosarcoma
antineoplastic agents
doxorubicin
methotrexate
Online Access:http://www.brazilianjournalofoncology.com.br/details/159/en-US/treatment-outcomes-for-adult-patients-with-localized-osteosarcoma-treated-with-chemotherapy-without-methotrexate-at-a-public-hospital-in-brazil
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