Treatment outcomes for patients with newly diagnosed or relapsed/refractory TP53-mutated mantle cell lymphoma: a systematic review and meta-analysisResearch in context

Treatment outcomes for patients with newly diagnosed or relapsed/refractory TP53-mutated mantle cell lymphoma: a systematic review and meta-analysisResearch in context

Summary: Background: TP53 mutation is a critical predictor of early disease progression and poor prognosis in mantle cell lymphoma (MCL). Optimal treatment for these patients remains unclear. This systematic review and meta-analysis evaluated various strategies for achieving remission in TP53-mutat...

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Bibliographic Details
Main Authors: Na Zhang, Jiegang Xu, Chengxin Luo, Rushuang Xu, Yan Zeng, Dongfeng Zeng, Shuangnian Xu, Xi Li
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:EClinicalMedicine
Subjects:
Mantle cell lymphoma
TP53 mutations
Remission strategies
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537025002688
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