Phosphodiesterase Type 4D Gene Polymorphism: Association with the Response to Short-Acting Bronchodilators in Paediatric Asthma Patients
Short-acting b2-adrenergic receptor agonists are commonly used bronchodilators for symptom relief in asthmatics. The aim of this study was to test whether genetic variants in PDE4D gene, a key regulator of b2-adrenoceptor-induced cAMP turnover in airway smooth muscle cells, affect the response to sh...
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| Main Authors: | Malgorzata Labuda, Sophie Laberge, Julie Brière, Denis Bérubé, Patrick Beaulieu, Tomi Pastinen, Maja Krajinovic |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2011/301695 |
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