Synergistic Autophagy-Related Mechanisms of Protection Against Brain Aging and AD: Cellular Pathways and Therapeutic Strategies

Synergistic Autophagy-Related Mechanisms of Protection Against Brain Aging and AD: Cellular Pathways and Therapeutic Strategies

Brain aging is driven by interconnected processes, including impaired autophagy, chronic inflammation, mitochondrial dysfunction, and cellular senescence, all of which contribute to neurovascular decline and neurodegenerative diseases such as Alzheimer’s disease (AD). Targeting these mechanisms simu...

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Bibliographic Details
Main Authors: Bogdan Cordos, Amelia Tero-Vescan, Ian N. Hampson, Anthony W. Oliver, Mark Slevin
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceuticals
Subjects:
Alzheimer’s disease
autophagy
neurodegeneration
metformin
benzimidazole
acetylsalicylic acid
Online Access:https://www.mdpi.com/1424-8247/18/6/829
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