A Bright Future for Immunotherapy: CAR T-Cell Therapy Promises Revolutionary Changes
Chimeric antigen receptor (CAR) T-cell therapy is an innovative technology that has fundamentally changed approaches to treating certain forms of oncological diseases. The anticipated development of CAR T cell-based therapies in the near future is expected to broaden the range of therapeutic targets...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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THE HEALTHBOOK COMPANY LTD.
2024-12-01
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| Series: | healthbook TIMES. Oncology Hematology |
| Online Access: | https://doi.org/10.36000/HBT.OH.2024.22.164 |
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| author | Viktoria A. Rybachuk Ekaterina S. Evstratova Ilja D. Klabukov Sergei A. Ivanov Petr V. Shegai Andrey D. Kaprin Denis S. Baranovsky |
| author_facet | Viktoria A. Rybachuk Ekaterina S. Evstratova Ilja D. Klabukov Sergei A. Ivanov Petr V. Shegai Andrey D. Kaprin Denis S. Baranovsky |
| author_sort | Viktoria A. Rybachuk |
| collection | DOAJ |
| description | Chimeric antigen receptor (CAR) T-cell therapy is an innovative technology that has fundamentally changed approaches to treating certain forms of oncological diseases. The anticipated development of CAR T cell-based therapies in the near future is expected to broaden the range of therapeutic targets and holds the potential to decrease treatment costs, thereby expanding accessibility for a broader patient population. This review article provides an overview of the practical applications of CAR T-cell therapy in clinical settings, describes the global market for commercial CAR T-cell products and offers insights into the future landscape of CAR T-cell therapy. We focus on emerging therapies, novel targets and strategic approaches to improve treatment efficacy and reduce costs. Furthermore, we discuss the progress of CAR T-cell therapy in Russia, where this type of therapy is in the early stages of development but already demonstrates promising potential.
PEER REVIEWED ARTICLE
**Peer reviewers:**
Dr Andriyana K. Bankova, National Specialized Hospital for Hematological Diseases, Sofia, Bulgaria
Erik Aerts, Hematology Nurses & Healthcare Professionals Group, University Hospital Zurich, Zurich, Switzerland
Received on November 06, 2024; accepted after peer review on December 28, 2024; published online on December 30, 2024. |
| format | Article |
| id | doaj-art-b3b514a74c3f4a8a9b86034e10933b52 |
| institution | DOAJ |
| issn | 2673-2092 2673-2106 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | THE HEALTHBOOK COMPANY LTD. |
| record_format | Article |
| series | healthbook TIMES. Oncology Hematology |
| spelling | doaj-art-b3b514a74c3f4a8a9b86034e10933b522025-08-20T03:14:35ZengTHE HEALTHBOOK COMPANY LTD.healthbook TIMES. Oncology Hematology2673-20922673-21062024-12-0122410.36000/HBT.OH.2024.22.164A Bright Future for Immunotherapy: CAR T-Cell Therapy Promises Revolutionary ChangesViktoria A. RybachukEkaterina S. EvstratovaIlja D. KlabukovSergei A. IvanovPetr V. ShegaiAndrey D. KaprinDenis S. BaranovskyChimeric antigen receptor (CAR) T-cell therapy is an innovative technology that has fundamentally changed approaches to treating certain forms of oncological diseases. The anticipated development of CAR T cell-based therapies in the near future is expected to broaden the range of therapeutic targets and holds the potential to decrease treatment costs, thereby expanding accessibility for a broader patient population. This review article provides an overview of the practical applications of CAR T-cell therapy in clinical settings, describes the global market for commercial CAR T-cell products and offers insights into the future landscape of CAR T-cell therapy. We focus on emerging therapies, novel targets and strategic approaches to improve treatment efficacy and reduce costs. Furthermore, we discuss the progress of CAR T-cell therapy in Russia, where this type of therapy is in the early stages of development but already demonstrates promising potential. PEER REVIEWED ARTICLE **Peer reviewers:** Dr Andriyana K. Bankova, National Specialized Hospital for Hematological Diseases, Sofia, Bulgaria Erik Aerts, Hematology Nurses & Healthcare Professionals Group, University Hospital Zurich, Zurich, Switzerland Received on November 06, 2024; accepted after peer review on December 28, 2024; published online on December 30, 2024.https://doi.org/10.36000/HBT.OH.2024.22.164 |
| spellingShingle | Viktoria A. Rybachuk Ekaterina S. Evstratova Ilja D. Klabukov Sergei A. Ivanov Petr V. Shegai Andrey D. Kaprin Denis S. Baranovsky A Bright Future for Immunotherapy: CAR T-Cell Therapy Promises Revolutionary Changes healthbook TIMES. Oncology Hematology |
| title | A Bright Future for Immunotherapy: CAR T-Cell Therapy Promises Revolutionary Changes |
| title_full | A Bright Future for Immunotherapy: CAR T-Cell Therapy Promises Revolutionary Changes |
| title_fullStr | A Bright Future for Immunotherapy: CAR T-Cell Therapy Promises Revolutionary Changes |
| title_full_unstemmed | A Bright Future for Immunotherapy: CAR T-Cell Therapy Promises Revolutionary Changes |
| title_short | A Bright Future for Immunotherapy: CAR T-Cell Therapy Promises Revolutionary Changes |
| title_sort | bright future for immunotherapy car t cell therapy promises revolutionary changes |
| url | https://doi.org/10.36000/HBT.OH.2024.22.164 |
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