Comparative analysis of oral microbiome in saliva samples of oral leukoplakia, proliferative leukoplakia and oral squamous cell carcinoma

Comparative analysis of oral microbiome in saliva samples of oral leukoplakia, proliferative leukoplakia and oral squamous cell carcinoma

BackgroundOral potentially malignant disorders (OPMDs), including conventional leukoplakia (OL) and proliferative verrucous leukoplakia (PVL), have distinct risks of progression to oral squamous cell carcinoma (OSCC). A role of the oral microbiome in this transformation is increasingly recognized, b...

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Bibliographic Details
Main Authors: Rossella Intini, Sol Balsells, Leticia Bagan, Giulio Fortuna, Herve Sroussi, Jose Bagan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oral Health
Subjects:
oral microbiome
oral leukoplakia
proliferative verrucous leukoplakia
oral squamous cell carcinoma
16S rRNA sequencing
microbial diversity
Online Access:https://www.frontiersin.org/articles/10.3389/froh.2025.1600090/full
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