PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injury
Abstract Investigating long-term posttraumatic stress disorder (PTSD) course and its predictors may guide prevention and early intervention strategies following trauma exposure, potentially reducing the long-lasting impact of trauma. N = 155 emergency-admitted adults with (suspected) serious injury...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-08-01
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| Series: | npj Mental Health Research |
| Online Access: | https://doi.org/10.1038/s44184-025-00153-7 |
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| author | Jeanet F. Karchoud Chris M. Hoeboer Irina Karaban Joanne Mouthaan Marit Sijbrandij Miranda Olff Rens van de Schoot Mirjam van Zuiden |
| author_facet | Jeanet F. Karchoud Chris M. Hoeboer Irina Karaban Joanne Mouthaan Marit Sijbrandij Miranda Olff Rens van de Schoot Mirjam van Zuiden |
| author_sort | Jeanet F. Karchoud |
| collection | DOAJ |
| description | Abstract Investigating long-term posttraumatic stress disorder (PTSD) course and its predictors may guide prevention and early intervention strategies following trauma exposure, potentially reducing the long-lasting impact of trauma. N = 155 emergency-admitted adults with (suspected) serious injury were repeatedly assessed until one-year post-trauma and completed a 12–15 year follow-up including a clinical PTSD interview. Adverse one-year PTSD trajectories; more exposure to additional potentially traumatic events and recent life stressors; and early post-trauma predictors (younger age, greater perceived impact of prior potentially traumatic events, higher heart rate) were significantly associated with higher PTSD symptom severity 12–15 years post-trauma. This study showed high consistency between one-year PTSD and its early post-trauma predictors with long-term PTSD outcomes. Early post-trauma predictors had predictive value up to 12–15 years. This suggests that early risk identification of one-year PTSD and subsequent effective early interventions also hold long-term beneficial effects for PTSD outcome. |
| format | Article |
| id | doaj-art-b3a378f0ad8b412aae59a572d74acdfa |
| institution | Kabale University |
| issn | 2731-4251 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Mental Health Research |
| spelling | doaj-art-b3a378f0ad8b412aae59a572d74acdfa2025-08-20T04:03:12ZengNature Portfolionpj Mental Health Research2731-42512025-08-01411910.1038/s44184-025-00153-7PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injuryJeanet F. Karchoud0Chris M. Hoeboer1Irina Karaban2Joanne Mouthaan3Marit Sijbrandij4Miranda Olff5Rens van de Schoot6Mirjam van Zuiden7Amsterdam UMC, University of Amsterdam, Psychiatry, Amsterdam Public HealthAmsterdam UMC, University of Amsterdam, Psychiatry, Amsterdam Public HealthAmsterdam UMC, University of Amsterdam, Psychiatry, Amsterdam Public HealthLeiden University, Department of Clinical PsychologyDepartment of Clinical, Neuro- and Developmental Psychology, WHO Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit AmsterdamAmsterdam UMC, University of Amsterdam, Psychiatry, Amsterdam Public HealthUtrecht University, Department of Methods and StatisticsAmsterdam UMC, University of Amsterdam, Psychiatry, Amsterdam Public HealthAbstract Investigating long-term posttraumatic stress disorder (PTSD) course and its predictors may guide prevention and early intervention strategies following trauma exposure, potentially reducing the long-lasting impact of trauma. N = 155 emergency-admitted adults with (suspected) serious injury were repeatedly assessed until one-year post-trauma and completed a 12–15 year follow-up including a clinical PTSD interview. Adverse one-year PTSD trajectories; more exposure to additional potentially traumatic events and recent life stressors; and early post-trauma predictors (younger age, greater perceived impact of prior potentially traumatic events, higher heart rate) were significantly associated with higher PTSD symptom severity 12–15 years post-trauma. This study showed high consistency between one-year PTSD and its early post-trauma predictors with long-term PTSD outcomes. Early post-trauma predictors had predictive value up to 12–15 years. This suggests that early risk identification of one-year PTSD and subsequent effective early interventions also hold long-term beneficial effects for PTSD outcome.https://doi.org/10.1038/s44184-025-00153-7 |
| spellingShingle | Jeanet F. Karchoud Chris M. Hoeboer Irina Karaban Joanne Mouthaan Marit Sijbrandij Miranda Olff Rens van de Schoot Mirjam van Zuiden PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injury npj Mental Health Research |
| title | PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injury |
| title_full | PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injury |
| title_fullStr | PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injury |
| title_full_unstemmed | PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injury |
| title_short | PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injury |
| title_sort | ptsd course and predictors in a 15 year longitudinal cohort following suspected serious injury |
| url | https://doi.org/10.1038/s44184-025-00153-7 |
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