Methods for diagnosing endothelial dysfunction

Endothelial dysfunction as a crucial factor in the pathogenesis of cardiovascular diseases requires precise and effective diagnostic methods. The review highlights the currently used methods which can be divided into morphological, instrumental, and laboratory ones. Special attention is paid to the...

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Bibliographic Details
Main Authors: A. V. Shabrov, A. S. Galenko, Yu. P. Uspensky, K. A. Loseva
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2021-07-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/4398
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Summary:Endothelial dysfunction as a crucial factor in the pathogenesis of cardiovascular diseases requires precise and effective diagnostic methods. The review highlights the currently used methods which can be divided into morphological, instrumental, and laboratory ones. Special attention is paid to the so called jar  test, which was  introduced by Professor V.A. Valdman in 1936. The jar test may  serve as a prototype of modern methods for endothelial function assessment.These diagnostic methods can help to identify functional endothelial disorders at the earliest stage. It will significantly expand the possibilities of primary prevention of cardiovascular and a number of other diseases through non-pharmacological and pharmacological correction of endothelial dysfunction.
ISSN:1682-0363
1819-3684