Type and physical intensity of occupations at pulmonary TB diagnosis

BACKGROUND: Pulmonary TB (PTB) predominantly affects individuals of working age. We sought to characterise the occupations of people newly diagnosed with PTB in Karachi, Pakistan, by type and physical intensity. DESIGN/METHODS: We did a secondary analysis of data from a study evaluating the diagnost...

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Main Authors: M. Saroufim, C. Geric, A. Majidulla, A. Abjani, G. Tavaziva, S. Saeed, A.J. Khan, F. Ahmad Khan
Format: Article
Language:English
Published: International Union Against Tuberculosis and Lung Disease (The Union) 2025-01-01
Series:IJTLD Open
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Online Access:https://www.ingentaconnect.com/contentone/iuatld/ijtldo/2025/00000002/00000001/art00008
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author M. Saroufim
C. Geric
A. Majidulla
A. Abjani
G. Tavaziva
S. Saeed
A.J. Khan
F. Ahmad Khan
author_facet M. Saroufim
C. Geric
A. Majidulla
A. Abjani
G. Tavaziva
S. Saeed
A.J. Khan
F. Ahmad Khan
author_sort M. Saroufim
collection DOAJ
description BACKGROUND: Pulmonary TB (PTB) predominantly affects individuals of working age. We sought to characterise the occupations of people newly diagnosed with PTB in Karachi, Pakistan, by type and physical intensity. DESIGN/METHODS: We did a secondary analysis of data from a study evaluating the diagnostic accuracy of artificial intelligence-based chest X-ray (CXR) analysis software, where individuals had been evaluated for active PTB using sputum cultures and had provided information on occupation. We used an accelerometer-validated US National Health and Nutrition Examination Survey-based job categorisation to assign physical activity levels to participant-reported occupations as High, Intermediate, or Low. RESULTS: Among 272 participants with microbiologically confirmed PTB (women: 130/272, 48%; median age: 29 years, IQR 22–45), 78% (211/272) had smear-positive disease, and 96% (260/272) had data on occupation. Unemployment was common (women: 70/122, 57%; men: 23/138, 17%). Most women reporting an occupation were homemakers (21/52, 40%), and 54% (28/52) had an intermediate- or a high physical activity occupation. Among men reporting an occupation, 35% (40/115) were labourers, and 79% (91/115) had an intermediate- or high-physical activity occupation. CONCLUSION: The majority of individuals with PTB were in their working age, had extensive disease, and had intermediate or high physical activity occupations, suggesting economic vulnerability due to physical impairment.
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spelling doaj-art-b39724b086e246349644b66f622c98e32025-01-23T13:39:30ZengInternational Union Against Tuberculosis and Lung Disease (The Union)IJTLD Open3005-75902025-01-0121394410.5588/ijtldopen.24.03238Type and physical intensity of occupations at pulmonary TB diagnosisM. Saroufim0C. Geric1A. Majidulla2A. Abjani3G. Tavaziva4S. Saeed5A.J. Khan6F. Ahmad Khan7Respiratory Epidemiology & Clinical Research Unit, Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada;Respiratory Epidemiology & Clinical Research Unit, Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada;Interactive Research and Development (IRD) Pakistan, Karachi, Pakistan;Interactive Research and Development (IRD) Pakistan, Karachi, Pakistan;Respiratory Epidemiology & Clinical Research Unit, Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada;The Indus Hospital, Karachi, Pakistan;IRD Global, Singapore;Respiratory Epidemiology & Clinical Research Unit, Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada;BACKGROUND: Pulmonary TB (PTB) predominantly affects individuals of working age. We sought to characterise the occupations of people newly diagnosed with PTB in Karachi, Pakistan, by type and physical intensity. DESIGN/METHODS: We did a secondary analysis of data from a study evaluating the diagnostic accuracy of artificial intelligence-based chest X-ray (CXR) analysis software, where individuals had been evaluated for active PTB using sputum cultures and had provided information on occupation. We used an accelerometer-validated US National Health and Nutrition Examination Survey-based job categorisation to assign physical activity levels to participant-reported occupations as High, Intermediate, or Low. RESULTS: Among 272 participants with microbiologically confirmed PTB (women: 130/272, 48%; median age: 29 years, IQR 22–45), 78% (211/272) had smear-positive disease, and 96% (260/272) had data on occupation. Unemployment was common (women: 70/122, 57%; men: 23/138, 17%). Most women reporting an occupation were homemakers (21/52, 40%), and 54% (28/52) had an intermediate- or a high physical activity occupation. Among men reporting an occupation, 35% (40/115) were labourers, and 79% (91/115) had an intermediate- or high-physical activity occupation. CONCLUSION: The majority of individuals with PTB were in their working age, had extensive disease, and had intermediate or high physical activity occupations, suggesting economic vulnerability due to physical impairment.https://www.ingentaconnect.com/contentone/iuatld/ijtldo/2025/00000002/00000001/art00008employmentphysical activitypost-tuberculosis lung disease
spellingShingle M. Saroufim
C. Geric
A. Majidulla
A. Abjani
G. Tavaziva
S. Saeed
A.J. Khan
F. Ahmad Khan
Type and physical intensity of occupations at pulmonary TB diagnosis
IJTLD Open
employment
physical activity
post-tuberculosis lung disease
title Type and physical intensity of occupations at pulmonary TB diagnosis
title_full Type and physical intensity of occupations at pulmonary TB diagnosis
title_fullStr Type and physical intensity of occupations at pulmonary TB diagnosis
title_full_unstemmed Type and physical intensity of occupations at pulmonary TB diagnosis
title_short Type and physical intensity of occupations at pulmonary TB diagnosis
title_sort type and physical intensity of occupations at pulmonary tb diagnosis
topic employment
physical activity
post-tuberculosis lung disease
url https://www.ingentaconnect.com/contentone/iuatld/ijtldo/2025/00000002/00000001/art00008
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