The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature
Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity. The low prevalence of patients with this cardiomyopathy presents a uniq...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/5172308 |
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| author | Courtney E. Bennett Ronald Freudenberger |
| author_facet | Courtney E. Bennett Ronald Freudenberger |
| author_sort | Courtney E. Bennett |
| collection | DOAJ |
| description | Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity. The low prevalence of patients with this cardiomyopathy presents a unique challenge for large, prospective trials to assess its pathogenesis, management, and outcomes. In this paper we review the embryology and genetics of LVNC, the diagnostic approach, and propose a management approach based on the current literature available. |
| format | Article |
| id | doaj-art-b37c99ed022d4a24abeb383c7ad44629 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-b37c99ed022d4a24abeb383c7ad446292025-02-03T01:08:05ZengWileyCardiology Research and Practice2090-80162090-05972016-01-01201610.1155/2016/51723085172308The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the LiteratureCourtney E. Bennett0Ronald Freudenberger1Mayo Clinic, 200 First Street SW, Rochester, MN 55902, USALehigh Valley Health Network, 1250 S Cedar Crest Boulevard, Allentown, PA 18103, USAIsolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity. The low prevalence of patients with this cardiomyopathy presents a unique challenge for large, prospective trials to assess its pathogenesis, management, and outcomes. In this paper we review the embryology and genetics of LVNC, the diagnostic approach, and propose a management approach based on the current literature available.http://dx.doi.org/10.1155/2016/5172308 |
| spellingShingle | Courtney E. Bennett Ronald Freudenberger The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature Cardiology Research and Practice |
| title | The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature |
| title_full | The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature |
| title_fullStr | The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature |
| title_full_unstemmed | The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature |
| title_short | The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature |
| title_sort | current approach to diagnosis and management of left ventricular noncompaction cardiomyopathy review of the literature |
| url | http://dx.doi.org/10.1155/2016/5172308 |
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