Association between oral mucosal lesions and xerostomia: a cross-sectional study in a Brazilian population sample
Abstract This study aimed to establish the frequency of oral mucosal conditions and xerostomia, identify a possible association between them, and verify their associated factors from a sample of the population of Três Corações, Brazil. A cross-sectional study was conducted with volunteers without ag...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Pesquisa Odontológica
2025-04-01
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| Series: | Brazilian Oral Research |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242025000101050&lng=en&tlng=en |
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| author | Soraya de Mattos Camargo GROSSMANN Luís Cláudio Santos PRADO Lorena de Andrade e SOUZA Dayane Priscila DOMINGUES Fábio Fernandes Borém BRUZINGA Laura Cascão LOPES Giovanna Ribeiro SOUTO |
| author_facet | Soraya de Mattos Camargo GROSSMANN Luís Cláudio Santos PRADO Lorena de Andrade e SOUZA Dayane Priscila DOMINGUES Fábio Fernandes Borém BRUZINGA Laura Cascão LOPES Giovanna Ribeiro SOUTO |
| author_sort | Soraya de Mattos Camargo GROSSMANN |
| collection | DOAJ |
| description | Abstract This study aimed to establish the frequency of oral mucosal conditions and xerostomia, identify a possible association between them, and verify their associated factors from a sample of the population of Três Corações, Brazil. A cross-sectional study was conducted with volunteers without age restriction. To evaluate the presence of oral mucosal conditions, an intra-oral examination was performed and a clinical diagnosis was established based on the official classifications of oral diseases. The report of xerostomia was identified by a validated questionnaire completed during anamnesis. Descriptive and association statistics were performed using a significance level of 5%. A total of 1,052 volunteers were evaluated. Oral mucosal lesions were observed in 42.11%, variations of normal structures in 38.50%, and xerostomia in 60.64%. Women were more affected than men, particularly women aged 20-49. Xerostomia was not found to be associated to oral mucosal conditions in general (p > 0.05); however, inflammatory fibrous hyperplasia (27.99%) and oral candidiasis (24.38%), the most prevalent lesions in the study, were associated with xerostomia (p < 0.001 and p = 0.006, respectively) and denture use (p = 0.025 and p < 0.001, respectively). Use of tobacco and alcohol intake were not associated with the presence of oral lesions (p = 0.319 and p = 0.739, respectively). The findings of this study are important for determining the prevalence of oral conditions and xerostomia in the general population, serving as a baseline for further investigations into the association between xerostomia, inflammatory fibrous hyperplasia, and oral candidiasis. |
| format | Article |
| id | doaj-art-b36caa2c75d3490d82ff0500543ce5bb |
| institution | OA Journals |
| issn | 1807-3107 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Sociedade Brasileira de Pesquisa Odontológica |
| record_format | Article |
| series | Brazilian Oral Research |
| spelling | doaj-art-b36caa2c75d3490d82ff0500543ce5bb2025-08-20T02:16:17ZengSociedade Brasileira de Pesquisa OdontológicaBrazilian Oral Research1807-31072025-04-013910.1590/1807-3107bor-2025.vol39.036Association between oral mucosal lesions and xerostomia: a cross-sectional study in a Brazilian population sampleSoraya de Mattos Camargo GROSSMANNhttps://orcid.org/0000-0002-8920-3853Luís Cláudio Santos PRADOhttps://orcid.org/0000-0003-1602-7876Lorena de Andrade e SOUZAhttps://orcid.org/0000-0002-1222-4824Dayane Priscila DOMINGUEShttps://orcid.org/0000-0002-7528-7371Fábio Fernandes Borém BRUZINGAhttps://orcid.org/0000-0002-0197-139XLaura Cascão LOPEShttps://orcid.org/0009-0000-4537-8865Giovanna Ribeiro SOUTOhttps://orcid.org/0000-0003-3617-8794Abstract This study aimed to establish the frequency of oral mucosal conditions and xerostomia, identify a possible association between them, and verify their associated factors from a sample of the population of Três Corações, Brazil. A cross-sectional study was conducted with volunteers without age restriction. To evaluate the presence of oral mucosal conditions, an intra-oral examination was performed and a clinical diagnosis was established based on the official classifications of oral diseases. The report of xerostomia was identified by a validated questionnaire completed during anamnesis. Descriptive and association statistics were performed using a significance level of 5%. A total of 1,052 volunteers were evaluated. Oral mucosal lesions were observed in 42.11%, variations of normal structures in 38.50%, and xerostomia in 60.64%. Women were more affected than men, particularly women aged 20-49. Xerostomia was not found to be associated to oral mucosal conditions in general (p > 0.05); however, inflammatory fibrous hyperplasia (27.99%) and oral candidiasis (24.38%), the most prevalent lesions in the study, were associated with xerostomia (p < 0.001 and p = 0.006, respectively) and denture use (p = 0.025 and p < 0.001, respectively). Use of tobacco and alcohol intake were not associated with the presence of oral lesions (p = 0.319 and p = 0.739, respectively). The findings of this study are important for determining the prevalence of oral conditions and xerostomia in the general population, serving as a baseline for further investigations into the association between xerostomia, inflammatory fibrous hyperplasia, and oral candidiasis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242025000101050&lng=en&tlng=enEpidemiologyMouth DiseasesMouth MucosaDiagnosis, OralXerostomia |
| spellingShingle | Soraya de Mattos Camargo GROSSMANN Luís Cláudio Santos PRADO Lorena de Andrade e SOUZA Dayane Priscila DOMINGUES Fábio Fernandes Borém BRUZINGA Laura Cascão LOPES Giovanna Ribeiro SOUTO Association between oral mucosal lesions and xerostomia: a cross-sectional study in a Brazilian population sample Brazilian Oral Research Epidemiology Mouth Diseases Mouth Mucosa Diagnosis, Oral Xerostomia |
| title | Association between oral mucosal lesions and xerostomia: a cross-sectional study in a Brazilian population sample |
| title_full | Association between oral mucosal lesions and xerostomia: a cross-sectional study in a Brazilian population sample |
| title_fullStr | Association between oral mucosal lesions and xerostomia: a cross-sectional study in a Brazilian population sample |
| title_full_unstemmed | Association between oral mucosal lesions and xerostomia: a cross-sectional study in a Brazilian population sample |
| title_short | Association between oral mucosal lesions and xerostomia: a cross-sectional study in a Brazilian population sample |
| title_sort | association between oral mucosal lesions and xerostomia a cross sectional study in a brazilian population sample |
| topic | Epidemiology Mouth Diseases Mouth Mucosa Diagnosis, Oral Xerostomia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242025000101050&lng=en&tlng=en |
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