Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource Countries
We present a rare case of gastrogastric intussusception due to gastrointestinal stromal tumor (GIST) and the largest comprehensive literature review of published case reports on gastrointestinal (GI) intussusception due to GIST in the past three decades. We found that the common presenting symptoms...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2018/1395230 |
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| _version_ | 1850159775996706816 |
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| author | Paddy Ssentongo Mark Egan Temitope E. Arkorful Theodore Dorvlo Oneka Scott John S. Oh Forster Amponsah-Manu |
| author_facet | Paddy Ssentongo Mark Egan Temitope E. Arkorful Theodore Dorvlo Oneka Scott John S. Oh Forster Amponsah-Manu |
| author_sort | Paddy Ssentongo |
| collection | DOAJ |
| description | We present a rare case of gastrogastric intussusception due to gastrointestinal stromal tumor (GIST) and the largest comprehensive literature review of published case reports on gastrointestinal (GI) intussusception due to GIST in the past three decades. We found that the common presenting symptoms were features of gastrointestinal obstruction and melena. We highlight the diagnostic challenges faced in low-resource countries. Our findings emphasize the importance of early clinical diagnosis in low-resource settings in order to guide timely management. In addition, histological analysis of the tumor for macroscopic and microscopic characteristics including mitotic index and c-Kit/CD117 status should be obtained to guide adjuvant therapy with imatinib mesylate. Periodic follow-up to access tumor recurrence is fundamental and should be the standard of care. |
| format | Article |
| id | doaj-art-b364163d98a540659ef8abce00a22ad3 |
| institution | OA Journals |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-b364163d98a540659ef8abce00a22ad32025-08-20T02:23:24ZengWileyCase Reports in Surgery2090-69002090-69192018-01-01201810.1155/2018/13952301395230Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource CountriesPaddy Ssentongo0Mark Egan1Temitope E. Arkorful2Theodore Dorvlo3Oneka Scott4John S. Oh5Forster Amponsah-Manu6Center for Neural Engineering, Department of Engineering, Science and Mechanics, Pennsylvania State University, University Park, PA, USADepartment of Pathology, Eastern Regional Hospital, P.O. Box 201, Koforidua, GhanaDepartment of Surgery, Eastern Regional Hospital, P.O. Box 201, Koforidua, GhanaDepartment of Surgery, Eastern Regional Hospital, P.O. Box 201, Koforidua, GhanaMinistry of Public Health, 1 Brickdam, Georgetown, GuyanaDepartment of Surgery, Penn State Hershey College of Medicine and Milton S. Hershey Medical Center, Hershey, PA, USADepartment of Surgery, Eastern Regional Hospital, P.O. Box 201, Koforidua, GhanaWe present a rare case of gastrogastric intussusception due to gastrointestinal stromal tumor (GIST) and the largest comprehensive literature review of published case reports on gastrointestinal (GI) intussusception due to GIST in the past three decades. We found that the common presenting symptoms were features of gastrointestinal obstruction and melena. We highlight the diagnostic challenges faced in low-resource countries. Our findings emphasize the importance of early clinical diagnosis in low-resource settings in order to guide timely management. In addition, histological analysis of the tumor for macroscopic and microscopic characteristics including mitotic index and c-Kit/CD117 status should be obtained to guide adjuvant therapy with imatinib mesylate. Periodic follow-up to access tumor recurrence is fundamental and should be the standard of care.http://dx.doi.org/10.1155/2018/1395230 |
| spellingShingle | Paddy Ssentongo Mark Egan Temitope E. Arkorful Theodore Dorvlo Oneka Scott John S. Oh Forster Amponsah-Manu Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource Countries Case Reports in Surgery |
| title | Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource Countries |
| title_full | Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource Countries |
| title_fullStr | Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource Countries |
| title_full_unstemmed | Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource Countries |
| title_short | Adult Intussusception due to Gastrointestinal Stromal Tumor: A Rare Case Report, Comprehensive Literature Review, and Diagnostic Challenges in Low-Resource Countries |
| title_sort | adult intussusception due to gastrointestinal stromal tumor a rare case report comprehensive literature review and diagnostic challenges in low resource countries |
| url | http://dx.doi.org/10.1155/2018/1395230 |
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