IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSION
Hypertension remains one of the main problems in modern medicine since it is a pathogenetic factor leading to a large number of cardiovascular diseases and premature death. The aim of the study is to measure and compare the levels of sulfhydryl groups in plasma and blood as well as reduced glutat...
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Danylo Halytsky Lviv National Medical University
2023-10-01
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| Series: | Acta Medica Leopoliensia |
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| Online Access: | https://amljournal.com/index.php/journal/article/view/327 |
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| author | Iryna Dronyk Roman Dutka Nathalia Chmyr Roman Pshyk Oksana Didenko |
| author_facet | Iryna Dronyk Roman Dutka Nathalia Chmyr Roman Pshyk Oksana Didenko |
| author_sort | Iryna Dronyk |
| collection | DOAJ |
| description | Hypertension remains one of the main problems in modern medicine since it is a pathogenetic factor leading to a large number of cardiovascular diseases and premature death.
The aim of the study is to measure and compare the levels of sulfhydryl groups in plasma and blood as well as reduced glutathione of erythrocytes in patients with stage II hypertension before and after engaging in a controlled physical exercise taking into account the intake of vitamin E and selenium.
Material and Methods. There were 60 patients with stage II hypertension and 30 relatively healthy individuals. The individuals under observation performed a two-stage physical exercise on a stationary bicycle ergometer with the intensity, corresponding to 50 and 75% of the maximum oxygen consumption by the body. The overall duration of each stage of the physical exercise accounted for 5 minutes with a three-minute break to rest in between. Blood was taken from the ulnar vein before the cardiac stress test and 5 minutes after it. The content of sulfhydryl groups in plasma and erythrocytes, as well as reduced glutathione of erythrocytes was measured in patients before and after the physical exercise. The examination was conducted twice - before and after the intake of vitamin E and selenium.
Results and Discussion. Since the immediate response to a cardiac stress test performed on a stationary bicycle is shown by changes in the level of non-protein-bound sulfhydryl groups of erythrocytes (the level decreases), it can be assumed that they are involved in the formation of the primary compensatory reaction in response to physical exercise in individuals suffering from arterial hypertension.
Conclusion. Thus, the decrease in the level of non-protein-bound sulfhydryl groups of erythrocytes enables to assess the degree of stress that affects the human body, as well as the antioxidant protection enhancement in patients with hypertension after taking vitamin E and selenium both before and after engaging in physical exercise. |
| format | Article |
| id | doaj-art-b361bf57bc4c41f3a5edfad8335ce50b |
| institution | Kabale University |
| issn | 1029-4244 2415-3303 |
| language | English |
| publishDate | 2023-10-01 |
| publisher | Danylo Halytsky Lviv National Medical University |
| record_format | Article |
| series | Acta Medica Leopoliensia |
| spelling | doaj-art-b361bf57bc4c41f3a5edfad8335ce50b2025-01-06T10:49:52ZengDanylo Halytsky Lviv National Medical UniversityActa Medica Leopoliensia1029-42442415-33032023-10-01291-2334810.25040/aml2023.1-2.033327IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSIONIryna Dronyk0Roman Dutka1Nathalia Chmyr2Roman Pshyk3Oksana Didenko4Danylo Halytsky Lviv National Medical University, Lviv, UkraineDanylo Halytsky Lviv National Medical University, Lviv, UkraineDanylo Halytsky Lviv National Medical University, Lviv, UkraineDanylo Halytsky Lviv National Medical University, Lviv, UkraineDanylo Halytsky Lviv National Medical University, Lviv, UkraineHypertension remains one of the main problems in modern medicine since it is a pathogenetic factor leading to a large number of cardiovascular diseases and premature death. The aim of the study is to measure and compare the levels of sulfhydryl groups in plasma and blood as well as reduced glutathione of erythrocytes in patients with stage II hypertension before and after engaging in a controlled physical exercise taking into account the intake of vitamin E and selenium. Material and Methods. There were 60 patients with stage II hypertension and 30 relatively healthy individuals. The individuals under observation performed a two-stage physical exercise on a stationary bicycle ergometer with the intensity, corresponding to 50 and 75% of the maximum oxygen consumption by the body. The overall duration of each stage of the physical exercise accounted for 5 minutes with a three-minute break to rest in between. Blood was taken from the ulnar vein before the cardiac stress test and 5 minutes after it. The content of sulfhydryl groups in plasma and erythrocytes, as well as reduced glutathione of erythrocytes was measured in patients before and after the physical exercise. The examination was conducted twice - before and after the intake of vitamin E and selenium. Results and Discussion. Since the immediate response to a cardiac stress test performed on a stationary bicycle is shown by changes in the level of non-protein-bound sulfhydryl groups of erythrocytes (the level decreases), it can be assumed that they are involved in the formation of the primary compensatory reaction in response to physical exercise in individuals suffering from arterial hypertension. Conclusion. Thus, the decrease in the level of non-protein-bound sulfhydryl groups of erythrocytes enables to assess the degree of stress that affects the human body, as well as the antioxidant protection enhancement in patients with hypertension after taking vitamin E and selenium both before and after engaging in physical exercise.https://amljournal.com/index.php/journal/article/view/327sulfhydryl groupsreduced glutathione of erythrocytesvitamin eseleniumphysical exercisearterial hypertension |
| spellingShingle | Iryna Dronyk Roman Dutka Nathalia Chmyr Roman Pshyk Oksana Didenko IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSION Acta Medica Leopoliensia sulfhydryl groups reduced glutathione of erythrocytes vitamin e selenium physical exercise arterial hypertension |
| title | IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSION |
| title_full | IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSION |
| title_fullStr | IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSION |
| title_full_unstemmed | IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSION |
| title_short | IMPACT OF VITAMIN E AND SELENIUM INTAKE ON ANTIOXIDANT PROTECTION INDICATORS DURING PHYSICAL EXERTION IN INDIVIDUALS WITH HYPERTENSION |
| title_sort | impact of vitamin e and selenium intake on antioxidant protection indicators during physical exertion in individuals with hypertension |
| topic | sulfhydryl groups reduced glutathione of erythrocytes vitamin e selenium physical exercise arterial hypertension |
| url | https://amljournal.com/index.php/journal/article/view/327 |
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