Isolated Splenic Tuberculosis without Any Radiological Focal Lesion
Incidence of tuberculosis (TB) of spleen is a rare entity and isolated splenic tuberculosis is an unusual phenomenon, especially in immunocompetent individuals. We came across a case of 63-year-old male who presented with high grade fever, loss of weight, and generalized weakness of one-month durati...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/130209 |
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| author | Sunil Raviraj A. Gogia A. Kakar S. P. Byotra |
| author_facet | Sunil Raviraj A. Gogia A. Kakar S. P. Byotra |
| author_sort | Sunil Raviraj |
| collection | DOAJ |
| description | Incidence of tuberculosis (TB) of spleen is a rare entity and isolated splenic tuberculosis is an unusual phenomenon, especially in immunocompetent individuals. We came across a case of 63-year-old male who presented with high grade fever, loss of weight, and generalized weakness of one-month duration. When physically examined, he had pallor and moderate nontender splenomegaly without any other significant clinical findings. He had pancytopenia, elevated ESR, and positive Mantoux test. Ultrasonography and CT scan of abdomen showed splenomegaly without any other relevant findings. Markers of connective tissue disorders and bone marrow aspiration and biopsy all were noncontributory for diagnosis. Hence splenic biopsy was done and sent for histopathological examination. Presence of caseation surrounded by epitheloid granulomas and Langerhans cells was suggestive of diagnosis as tuberculosis. And gene probe for the AFB (acid fast bacilli) came to be positive. No primary focus was present in either lungs or other organs. Patient improved clinically with antitubercular treatment. |
| format | Article |
| id | doaj-art-b35ea730302c4a9b973c9bb54b674ac8 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-b35ea730302c4a9b973c9bb54b674ac82025-08-20T03:39:19ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/130209130209Isolated Splenic Tuberculosis without Any Radiological Focal LesionSunil Raviraj0A. Gogia1A. Kakar2S. P. Byotra3Department of Medicine, Ganga Ram Institute of Postgraduate Medical Education and Research Center (GRIPMER), Sir Ganga Ram Hospital, New Delhi 110060, IndiaDepartment of Medicine, Ganga Ram Institute of Postgraduate Medical Education and Research Center (GRIPMER), Sir Ganga Ram Hospital, New Delhi 110060, IndiaDepartment of Medicine, Ganga Ram Institute of Postgraduate Medical Education and Research Center (GRIPMER), Sir Ganga Ram Hospital, New Delhi 110060, IndiaDepartment of Medicine, Ganga Ram Institute of Postgraduate Medical Education and Research Center (GRIPMER), Sir Ganga Ram Hospital, New Delhi 110060, IndiaIncidence of tuberculosis (TB) of spleen is a rare entity and isolated splenic tuberculosis is an unusual phenomenon, especially in immunocompetent individuals. We came across a case of 63-year-old male who presented with high grade fever, loss of weight, and generalized weakness of one-month duration. When physically examined, he had pallor and moderate nontender splenomegaly without any other significant clinical findings. He had pancytopenia, elevated ESR, and positive Mantoux test. Ultrasonography and CT scan of abdomen showed splenomegaly without any other relevant findings. Markers of connective tissue disorders and bone marrow aspiration and biopsy all were noncontributory for diagnosis. Hence splenic biopsy was done and sent for histopathological examination. Presence of caseation surrounded by epitheloid granulomas and Langerhans cells was suggestive of diagnosis as tuberculosis. And gene probe for the AFB (acid fast bacilli) came to be positive. No primary focus was present in either lungs or other organs. Patient improved clinically with antitubercular treatment.http://dx.doi.org/10.1155/2015/130209 |
| spellingShingle | Sunil Raviraj A. Gogia A. Kakar S. P. Byotra Isolated Splenic Tuberculosis without Any Radiological Focal Lesion Case Reports in Medicine |
| title | Isolated Splenic Tuberculosis without Any Radiological Focal Lesion |
| title_full | Isolated Splenic Tuberculosis without Any Radiological Focal Lesion |
| title_fullStr | Isolated Splenic Tuberculosis without Any Radiological Focal Lesion |
| title_full_unstemmed | Isolated Splenic Tuberculosis without Any Radiological Focal Lesion |
| title_short | Isolated Splenic Tuberculosis without Any Radiological Focal Lesion |
| title_sort | isolated splenic tuberculosis without any radiological focal lesion |
| url | http://dx.doi.org/10.1155/2015/130209 |
| work_keys_str_mv | AT sunilraviraj isolatedsplenictuberculosiswithoutanyradiologicalfocallesion AT agogia isolatedsplenictuberculosiswithoutanyradiologicalfocallesion AT akakar isolatedsplenictuberculosiswithoutanyradiologicalfocallesion AT spbyotra isolatedsplenictuberculosiswithoutanyradiologicalfocallesion |