Relapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy
Introduction. Takayasu arteritis (TA) is a rare large vessel arteritis, affecting primarily aorta and its major branches. Its clinical manifestations can vary significantly - from asymptomatic to serious vascular events. Acute neurological complications are frequent at the onset of the dise...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2016-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501500092K.pdf |
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| author | Komatina Nenad Lepić Toplica Labović Boban Stevović Tatjana Petronijević Milan Radovinović-Tasić Sanja Obradović Dragana |
| author_facet | Komatina Nenad Lepić Toplica Labović Boban Stevović Tatjana Petronijević Milan Radovinović-Tasić Sanja Obradović Dragana |
| author_sort | Komatina Nenad |
| collection | DOAJ |
| description | Introduction. Takayasu arteritis (TA) is a rare large vessel arteritis,
affecting primarily aorta and its major branches. Its clinical manifestations
can vary significantly - from asymptomatic to serious vascular events. Acute
neurological complications are frequent at the onset of the disease and in
relapses. Anxiety and depression are more frequent in TA patients than in
general population as well as during relapses. Prevalence of transient
ischemic attack or ischemic stroke in TA patients is approximately 10-20%.
Case report. We presented a patient with TA that began with a depressive
episode resulting in attempted suicide by bromazepame poisoning. This was
subsequently followed by major ischemic stroke caused by thrombosis of the
left middle cerebral artery (probably due to aortic arch embolism)
successfully treated with intravenous thrombolysis. Conclusion. Intravenous
thrombolysis appears to be safe and effective in patients with TA and stroke. |
| format | Article |
| id | doaj-art-b35489b282e2444b95b5ec043b93e332 |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-b35489b282e2444b95b5ec043b93e3322025-08-20T02:23:24ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202016-01-0173878879210.2298/VSP150717092K0042-84501500092KRelapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapyKomatina Nenad0Lepić Toplica1Labović Boban2Stevović Tatjana3Petronijević Milan4Radovinović-Tasić Sanja5Obradović Dragana6Military Medical Academy, Neurology Clinic, BelgradeMilitary Medical Academy, Neurology Clinic, BelgradeMilitary Medical Academy, Neurology Clinic, BelgradeMilitary Medical Academy, Toxicology Clinic, BelgradeMilitary Medical Academy, Rheumatology Clinic, Belgrade + Military Medical Academy, Institute of Radiology, Belgrade + University of Defense, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Toxicology Clinic, BelgradeMilitary Medical Academy, Neurology Clinic, Belgrade + Military Medical Academy, Institute of Radiology, Belgrade + University of Defense, Faculty of Medicine of the Military Medical Academy, BelgradeIntroduction. Takayasu arteritis (TA) is a rare large vessel arteritis, affecting primarily aorta and its major branches. Its clinical manifestations can vary significantly - from asymptomatic to serious vascular events. Acute neurological complications are frequent at the onset of the disease and in relapses. Anxiety and depression are more frequent in TA patients than in general population as well as during relapses. Prevalence of transient ischemic attack or ischemic stroke in TA patients is approximately 10-20%. Case report. We presented a patient with TA that began with a depressive episode resulting in attempted suicide by bromazepame poisoning. This was subsequently followed by major ischemic stroke caused by thrombosis of the left middle cerebral artery (probably due to aortic arch embolism) successfully treated with intravenous thrombolysis. Conclusion. Intravenous thrombolysis appears to be safe and effective in patients with TA and stroke.http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501500092K.pdfTakayasu arteritisrecurrencepoisoningsuicide, attemptedthrombosismiddle cerebral arterytissue plasminogen activatortreatment outcomedepression |
| spellingShingle | Komatina Nenad Lepić Toplica Labović Boban Stevović Tatjana Petronijević Milan Radovinović-Tasić Sanja Obradović Dragana Relapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy Vojnosanitetski Pregled Takayasu arteritis recurrence poisoning suicide, attempted thrombosis middle cerebral artery tissue plasminogen activator treatment outcome depression |
| title | Relapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy |
| title_full | Relapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy |
| title_fullStr | Relapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy |
| title_full_unstemmed | Relapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy |
| title_short | Relapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy |
| title_sort | relapse of takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy |
| topic | Takayasu arteritis recurrence poisoning suicide, attempted thrombosis middle cerebral artery tissue plasminogen activator treatment outcome depression |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501500092K.pdf |
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