Relapse of Takayasu arteritis as a cause of suicidal poisoning and subsequent major ischemic stroke successfully treated with thrombolytic therapy
Introduction. Takayasu arteritis (TA) is a rare large vessel arteritis, affecting primarily aorta and its major branches. Its clinical manifestations can vary significantly - from asymptomatic to serious vascular events. Acute neurological complications are frequent at the onset of the dise...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2016-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501500092K.pdf |
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| Summary: | Introduction. Takayasu arteritis (TA) is a rare large vessel arteritis,
affecting primarily aorta and its major branches. Its clinical manifestations
can vary significantly - from asymptomatic to serious vascular events. Acute
neurological complications are frequent at the onset of the disease and in
relapses. Anxiety and depression are more frequent in TA patients than in
general population as well as during relapses. Prevalence of transient
ischemic attack or ischemic stroke in TA patients is approximately 10-20%.
Case report. We presented a patient with TA that began with a depressive
episode resulting in attempted suicide by bromazepame poisoning. This was
subsequently followed by major ischemic stroke caused by thrombosis of the
left middle cerebral artery (probably due to aortic arch embolism)
successfully treated with intravenous thrombolysis. Conclusion. Intravenous
thrombolysis appears to be safe and effective in patients with TA and stroke. |
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| ISSN: | 0042-8450 2406-0720 |